CTX-M producing carbapenem- resistant Klebsiella pneumonia from children with upper respiratory tract infections in Hilla City

Author

Abbas, Fatimah Muin

Source

Mesopotamia Environment Journal

Publisher

University of Babylon Environmental Research and Studies Center

Publication Date

2017-12-31

Country of Publication

Iraq

No. of Pages

7

Main Subjects

Natural & Life Sciences (Multidisciplinary)

English Abstract

This study was attempted to find out the prevalence of blaCTX-M gene among carbapenem resistant Klebsiella pneumoniae from upper respiratory tract infections .

In total ,100 throat samples were collected from children attending Babylon Teaching Hospital for Maternity and Pediatric at a period from November, 2015 to the end of February, 2016 .Fourteenth (14 %) isolates were specified as K.pneumoniae, these were screened phenotypically for extended spectrum β-lactamase (ESBL) production by disk combination method.

Nine (64.3 %) isolates were found to be screen-positive.

ESBL-producing isolates were submitted to antimicrobial susceptibility testing using Kirby-Bauer disk diffusion method.

The highest rates of resistance were observed for penicillin antibiotics (ampicillin and cloxacillin) with (88.88 %) and (77.77 %) resistance rate, respectively.

The lowest rate for carbapenem antibiotics (imipenem, 11.11 % and meropenem, 22.22 %).

Carbapenem resistant isolates were checked by Polymerase Chain Reaction (PCR) method for the presence of blaCTX-M , 2 (100 %) isolates gave positive result.

Data Type

Conference Papers

Record ID

BIM-787079

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