Immunological response of locally prepared oil adjuvanted pneumo-5 vaccine in calves
Joint Authors
al-Hawwari, Rasha I.
Mustafa, Hana A.
Source
Journal of Veterinary Medical Research
Issue
Vol. 24, Issue 1 (30 Jun. 2017)7 p.
Publisher
Beni-Suef University Faculty of Veterinary Medicine
Publication Date
2017-06-30
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The present study aimed to prepare a combined inactivated vaccine containing bovine viral diarrhea genotype-1(BVD-1),bovine viral diarrhea genotype-2 (BVD-2),infectious bovine rhinotracheitis (IBR),parainfluenza-3 (PI-3) and bovine respiratory syncytial virus(BRSV) and adjuvanted with montanide oil ISA 206.
Quality control results proved that the pneumo-5 vaccine was pure and completely safe to be used in calves without abnormalities.
Potency test was performed on two groups of calves three for each group, where the first group was vaccinated with pneumo-5 vaccine adjuvant with montanide oil ISA 206 and the second group was left as non-vaccinated control group.
In group (1), serum neutralization test revealed that the serum neutralizing antibody titers in BVD-1 and BVD-2 developed more higher than the minimal acceptable titer of the protective level (log10 0.9), while log10 0.6 was protective against IBR, PI-3 and BRS viruses at one month of vaccination and remained protective till the end of experiment compared to group (2) that showed no neutralizing antibody response.
The prepared vaccine proved to be highly potent as the developed BVD-1, BVD-2, IBR, PI-3 and BRSV antibodies remained within the protective level for 9 months post vaccination.
American Psychological Association (APA)
al-Hawwari, Rasha I.& Mustafa, Hana A.. 2017. Immunological response of locally prepared oil adjuvanted pneumo-5 vaccine in calves. Journal of Veterinary Medical Research،Vol. 24, no. 1.
https://search.emarefa.net/detail/BIM-787862
Modern Language Association (MLA)
al-Hawwari, Rasha I.& Mustafa, Hana A.. Immunological response of locally prepared oil adjuvanted pneumo-5 vaccine in calves. Journal of Veterinary Medical Research Vol. 24, no. 1 (2017).
https://search.emarefa.net/detail/BIM-787862
American Medical Association (AMA)
al-Hawwari, Rasha I.& Mustafa, Hana A.. Immunological response of locally prepared oil adjuvanted pneumo-5 vaccine in calves. Journal of Veterinary Medical Research. 2017. Vol. 24, no. 1.
https://search.emarefa.net/detail/BIM-787862
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-787862