Nano-SiO2 catalyzed three-component preparations of pyrano [2, 3-d)‎]pyrimidines, 4H-chromenes, and dihydropyrano [3, 2-c] chromenes

Abstract EN

An efficient one-pot three-component procedure has been developed for the preparation of tetrahydrobenzo[b]pyrans, dihydropyrano[3,2-c]chromenes, and pyrano[2,3-d]pyrimidines using nano-SiO2 as catalyst in H2O at 70 C.

This methodology has a number of advantages such as: use of reusable catalyst, easy access, short reaction times, high yields, easy work up and use of non-toxic and green solvent.