Osteosarcoma subtypes : magnetic resonance and quantitative diffusion weighted imaging criteria
Joint Authors
Khalil, Sahar A.
Zaytun, Raniya
Shukri, Ahmad M.
Mujahid, Shayma M.
Source
Journal of the Egyptian National Cancer Institute
Issue
Vol. 30, Issue 1 (31 Jan. 2018), pp.39-44, 6 p.
Publisher
Cairo University National Cancer Institute
Publication Date
2018-01-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
-Introduction: Osteosarcoma (OS) is a primary bone malignancy, characterized by spindle cells producing osteoid.
The objective of this study is to describe the magnetic resonance imaging (MRI) features of different OS subtypes, record their attenuation diffusion coefficient (ADC) values and to point to the relation of their pathologic base and their corresponding ADC value.
Patients and methods: We performed a retrospective observational lesion-based analysis for 31 pathologically proven osteosarcoma subtypes: osteoblastic (n = 9), fibroblastic (n = 8), chondroblastic (n = 6), para-osteal (n = 3), periosteal (n = 1), telangiectatic (n = 2), small cell (n = 1) and extra-skeletal (n = 1).
On conventional images we recorded: bone of origin, epicenter, intra-articular extension, and invasion of articulating bones, skip lesions, distant metastases, pathological fractures, ossified matrix, hemorrhage and necrosis.
We measured the mean ADC value for each lesion.
Results: Among the included OS lesions, 51.6% originated at the femur, 29% showed intra-articular extension, 16% invaded neighboring bone, 9% were associated with pathological fracture and 25.8% were associated with distant metastases.
On MRI, all lesions showed ossified matrix, 35.5% showed hemorrhage and 58% showed necrosis.
The mean ADC values for OS lesions ranged from 0.74 103 mm2/s (recorded for conventional osteoblastic OS) to 1.50 103 mm2/s (recorded for telangiectatic OS) with an average value of 1.16 ± 0.18 103 mm2/s.
Conventional chondroblastic OS recorded higher values compared to the other two conventional subtypes.
Conclusion: Osteosarcoma has different pathologic subtypes which correspondingly vary in their imaging criteria and their ADC values.
American Psychological Association (APA)
Zaytun, Raniya& Shukri, Ahmad M.& Khalil, Sahar A.& Mujahid, Shayma M.. 2018. Osteosarcoma subtypes : magnetic resonance and quantitative diffusion weighted imaging criteria. Journal of the Egyptian National Cancer Institute،Vol. 30, no. 1, pp.39-44.
https://search.emarefa.net/detail/BIM-789055
Modern Language Association (MLA)
Zaytun, Raniya…[et al.]. Osteosarcoma subtypes : magnetic resonance and quantitative diffusion weighted imaging criteria. Journal of the Egyptian National Cancer Institute Vol. 30, no. 1 (Jan. 2018), pp.39-44.
https://search.emarefa.net/detail/BIM-789055
American Medical Association (AMA)
Zaytun, Raniya& Shukri, Ahmad M.& Khalil, Sahar A.& Mujahid, Shayma M.. Osteosarcoma subtypes : magnetic resonance and quantitative diffusion weighted imaging criteria. Journal of the Egyptian National Cancer Institute. 2018. Vol. 30, no. 1, pp.39-44.
https://search.emarefa.net/detail/BIM-789055
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 43-44
Record ID
BIM-789055