Osteosarcoma of the jaw : challenges in the diagnosis and treatment
Joint Authors
al-Kurdi, Muhammad Atif
al-Baradii, Tariq Sharif
Khayr Allah, Sharif Muhammad
Amin, Ayman Abd al-Wahhab
al-Sibai, Hisham Ismail
Source
Journal of the Egyptian National Cancer Institute
Issue
Vol. 30, Issue 1 (31 Jan. 2018), pp.7-11, 5 p.
Publisher
Cairo University National Cancer Institute
Publication Date
2018-01-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Purpose : Osteosarcomas rarely affect jaw bones.
Patients are usually older than those who suffer long bone sarcomas, with a rare incidence of metastasis.
This is suggestive of a different pattern of behavior compared with long bone sarcomas.
This study aimed to present NCI, Cairo University experience in treating patients diagnosed with osteosarcomas of the jaw, including the diagnostic challenges and treatment outcome.
Patients and methods : This is a retrospective case series study of all cases of osteosarcomas of mandible and maxilla that were treated at the NCI, in the period between 2006 and 2013.
Patients’ data, including demographic data, various clinical presentations, results of investigations, treatment modalities performed and outcomes, were collected from hospital records kept in the Biostatistics Department at NCI.
Results : Records showed 21 cases of osteosarcoma of the jaw.
The mandible was affected in 15 cases, the maxilla in six.
Two cases had sun-ray periosteal reactions.
Erroneous biopsy results were found in 4 cases compared with final pathology reports of surgical resections.
All cases underwent surgical resections, with 8 cases having positive margins.
The median follow-up period was 19.3 months (range 0.3–98.0 months).
The cumulative disease-free survival (DFS) was 27.5% and the median DFS was 72 months.
The cumulative overall survival at end of the study was 77.4%.
Conclusions : Osteosarcoma of the jaw is challenging both to diagnose and manage.
This is due to the high incidence of mistakes in biopsy results, rare specific radiological features and difficulties in proper resection due to proximity to vital structures
American Psychological Association (APA)
al-Kurdi, Muhammad Atif& al-Baradii, Tariq Sharif& al-Sibai, Hisham Ismail& Amin, Ayman Abd al-Wahhab& Khayr Allah, Sharif Muhammad. 2018. Osteosarcoma of the jaw : challenges in the diagnosis and treatment. Journal of the Egyptian National Cancer Institute،Vol. 30, no. 1, pp.7-11.
https://search.emarefa.net/detail/BIM-789056
Modern Language Association (MLA)
al-Kurdi, Muhammad Atif…[et al.]. Osteosarcoma of the jaw : challenges in the diagnosis and treatment. Journal of the Egyptian National Cancer Institute Vol. 30, no. 1 (Jan. 2018), pp.7-11.
https://search.emarefa.net/detail/BIM-789056
American Medical Association (AMA)
al-Kurdi, Muhammad Atif& al-Baradii, Tariq Sharif& al-Sibai, Hisham Ismail& Amin, Ayman Abd al-Wahhab& Khayr Allah, Sharif Muhammad. Osteosarcoma of the jaw : challenges in the diagnosis and treatment. Journal of the Egyptian National Cancer Institute. 2018. Vol. 30, no. 1, pp.7-11.
https://search.emarefa.net/detail/BIM-789056
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 10-11
Record ID
BIM-789056