The efficacy of mentha longifolia in the treatment of patients with postprandial distress syndrome : a double-blind, randomized clinical trial
Joint Authors
Babaeian, Mahmud
Ghaffari, Farzaneh
Rafi, Rahmah Allah
Mazahiri, Muhammad
Park, Jae Woo
Adibi, Peyman
Kamalinejad, Muhammad
Nasiri, Muhsin
Imadi, Fatimah
Hasheminejad, Sayyid Abbas
Feizi, Awat
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 19, Issue 2 (28 Feb. 2017), pp.1-10, 10 p.
Publisher
Publication Date
2017-02-28
Country of Publication
United Arab Emirates
No. of Pages
10
Main Subjects
Abstract EN
Background: Functional dyspepsia (FD) is a common gastrointestinal disease that has various treatments, including medicinal plants.
Objectives: The current study aimed to investigate the effect of Mentha longifolia on relieving the symptoms and improving the quality of life (QOL) in patients with functional dyspepsia from the subgroup of postprandial distress syndrome (PDS).
Patients and Methods: This randomized, double-blind, placebo-controlled trial was conducted in a gastroenterology clinic affiliated with Isfahan University of Medical Sciences.
One hundred patients diagnosed with PDS according to the ROME III criteria were assigned to two groups: the M.
longifolia capsules (three times daily for four weeks) group and the placebo group.
Tools for gathering data were the FD severity scale and QOL (Persian version of the SF-36 questionnaire).
Assessments of FD symptoms were obtained at baseline and also at the end of weeks 2, 4, and 12.
QOL was evaluated at baseline and at the end of week 12.
Results: At the end of treatment period, the M.
longifolia group reported a more significant improvement in themeanseverity scales of FD symptoms than the placebo group (P < 0.001).
A significant difference was also observed between FD symptoms and severity scores in the two groups eight weeks after the medication was stopped.
At the end of the fourth week, the greatest degrees of relief regarding epigastric bloating (70.5% vs.
21.4%, P < 0.001), epigastric fullness (68.2% vs.
31%, P < 0.001), loss of appetite (34.1% vs.
9.5%, P = 0.014) and early satiety (36.3% vs.
21.4%, P = 0.02) were observed in the control group.
With M.
longifolia, significant improvement in the scores of QOL was observed for the dimensions of general health, role-physical, social functioning, bodily pain, vitality, and mental health.
American Psychological Association (APA)
Babaeian, Mahmud& Nasiri, Muhsin& Kamalinejad, Muhammad& Ghaffari, Farzaneh& Imadi, Fatimah& Feizi, Awat…[et al.]. 2017. The efficacy of mentha longifolia in the treatment of patients with postprandial distress syndrome : a double-blind, randomized clinical trial. Iranian Red Crescent Medical Journal،Vol. 19, no. 2, pp.1-10.
https://search.emarefa.net/detail/BIM-791783
Modern Language Association (MLA)
Babaeian, Mahmud…[et al.]. The efficacy of mentha longifolia in the treatment of patients with postprandial distress syndrome : a double-blind, randomized clinical trial. Iranian Red Crescent Medical Journal Vol. 19, no. 2 (Feb. 2017), pp.1-10.
https://search.emarefa.net/detail/BIM-791783
American Medical Association (AMA)
Babaeian, Mahmud& Nasiri, Muhsin& Kamalinejad, Muhammad& Ghaffari, Farzaneh& Imadi, Fatimah& Feizi, Awat…[et al.]. The efficacy of mentha longifolia in the treatment of patients with postprandial distress syndrome : a double-blind, randomized clinical trial. Iranian Red Crescent Medical Journal. 2017. Vol. 19, no. 2, pp.1-10.
https://search.emarefa.net/detail/BIM-791783
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 9-10
Record ID
BIM-791783