![](/images/graphics-bg.png)
A comparison of the effects of low and high doses of aminophylline on recovery time and the bispectral index score following iso flurane anesthesia
Joint Authors
Imani, Farsad
Tabatabaei, Azadeh Ahmadi
Moharari, Rida Shariat
Etezadi, Farhad
Pourfakhr, Pejman
Khajavi, Muhammad Rida
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 19, Issue 2 (28 Feb. 2017), pp.1-5, 5 p.
Publisher
Publication Date
2017-02-28
Country of Publication
United Arab Emirates
No. of Pages
5
Main Subjects
Abstract EN
Background: Aminophylline expedites the recovery from total intravenous and inhalation anesthesia.
Objectives: The aim of this study was to evaluate low and high doses of aminophylline on extubation time, time to discharge from recovery, and the bispectral index score (BIS) in patients who received isoflurane anesthesia.
Patients and Methods: After ethical approval and informed consent were obtained, this prospective, randomized, blinded clinical study was conducted in Sina hospital in Iran.
Seventy-five patients who were scheduled for elective laparatomy surgery under isoflurane anesthesia were randomly allocated to receive either saline or 1 or 5 mg/kg of aminophylline (n = 25 for each) at the end of their anesthesia.
The time to tracheal extubation and BIS after the administration of the study drug and the total time required until discharge from the post anesthesia care unit (PACU) were recorded.
Results: Seventy-five patients completed the study.
Compared to saline, patients who received 1 and 5 mg/kg of aminophylline demonstrated decreased extubation times (meanSD) (12.267.33 vs.
11.158.62 and 10.44.78 min, respectively, P = 0.001) with higher BIS values (P=0.001).
However, the recoveryanddischarge timesfromthePACUwerenodifferent between the aminophylline and saline groups.
Conclusions: The administration of high doses of aminophylline after laparatomy procedures with isoflurane anesthesia expedited the extubation time with no effects on discharge from the PACU.
American Psychological Association (APA)
Imani, Farsad& Tabatabaei, Azadeh Ahmadi& Moharari, Rida Shariat& Etezadi, Farhad& Pourfakhr, Pejman& Khajavi, Muhammad Rida. 2017. A comparison of the effects of low and high doses of aminophylline on recovery time and the bispectral index score following iso flurane anesthesia. Iranian Red Crescent Medical Journal،Vol. 19, no. 2, pp.1-5.
https://search.emarefa.net/detail/BIM-791793
Modern Language Association (MLA)
Imani, Farsad…[et al.]. A comparison of the effects of low and high doses of aminophylline on recovery time and the bispectral index score following iso flurane anesthesia. Iranian Red Crescent Medical Journal Vol. 19, no. 2 (Feb. 2017), pp.1-5.
https://search.emarefa.net/detail/BIM-791793
American Medical Association (AMA)
Imani, Farsad& Tabatabaei, Azadeh Ahmadi& Moharari, Rida Shariat& Etezadi, Farhad& Pourfakhr, Pejman& Khajavi, Muhammad Rida. A comparison of the effects of low and high doses of aminophylline on recovery time and the bispectral index score following iso flurane anesthesia. Iranian Red Crescent Medical Journal. 2017. Vol. 19, no. 2, pp.1-5.
https://search.emarefa.net/detail/BIM-791793
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 4-5
Record ID
BIM-791793