Hot aqueous of matricaria chamomilla extract modulate nephritic toxicity induced by methomyl in male mice

Abstract EN

This projects was planning to evaluate the effects of oral administration of hot aqueous extract of (Matricaria chamomilla plant) on the chemical parameters of the kidney in male mice treated with different dose of metomil (methomyl insecticide).

Eighteen mice was parting into 6 groups of 3 animals in every one.

The study was performed for 28 days and the alterations of the parameters were measured any changings in the weight of kidney , urea and creatninin concentration.

The study was revealed a significant increasing in the kidneys weight, levels of serum urea and creatinin of mice treated with methomyl only when compared with control.

The results also show the increasing recorded above began to decrease gradually after the mice treated with hot aqueous extract of chamomile with (5 and 7mg/kg b.w) concentrations .

This result draw attention to the ability of chamomile extract to modulate the toxic effects of methomyl on kidney