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The role of proinflammatory cytokines and some hormones in endometriosis-induced osteoporosis
Other Title(s)
دور الساينوكيناتالموالية للالتهابات و بعض الهرمونات في حدوث هشاشة العظام لدي مريضات الانتباذ البطاني الرحمي
Joint Authors
al-Yasin, Firas Fadil
Tahir, Muhammad Abbas
Source
Issue
Vol. 9, Issue 1 (31 Dec. 2015)18 p.
Publisher
University of Thi-Qar College of Medicine
Publication Date
2015-12-31
Country of Publication
Iraq
No. of Pages
18
Main Subjects
Abstract EN
Objective: The aim of this study is to evaluate the effects of proinflammatory cytokines and some hormones, in patients with endometriosis, on the serum levels of bone formation and bone resorption markers.
Subjects and methods: Eightyfemale patients with endometriosis at their reproductive age subjected to standard criteria were participated in this study.
Eighty apparently healthy women were selected to be a normal group for comparison.
In addition, assessing the serum levels of tumor necrosis factor alpha [TNF-α], interleukin 1[IL-1], interleukin 6 [IL-6], CarboxyterminalTelopeptides of type I Collagen [CTX1], CarboxyterminalPropeptide of type I Procollagen [PICP], Estradiol [E2], Follicle-Stimulating Hormone [FSH], Thyroid-Stimulating Hormone [TSH], and Parathyroid Hormone [PTH] by EILISA and enzymatic Kits.
Results: The results show that the levels of tumor necrosis factor alpha [TNF-α], interleukin 1[IL-1] , interleukin 6[IL-6], C terminal Telopeptides of type I Collagen[CTX1]and C terminal propeptide of type I procollagen[PICP], follicle-stimulating hormone [FSH], thyroid-stimulating hormone [TSH] and parathyroid hormone [PTH] weresignificantly changed in serum of patients with endometriosisas compared with control healthy group.
Whereas, the change of serum estradiol [E2] level was non-significant as compared with control group.
Conclusions: The inflammatory activity of tumor necrosis factor alpha [TNF-α], interleukin 1[IL-1] and interleukin 6 [IL-6] was important in the development of osteoporosis in patients with endometriosisby its effect on bone formation and resorption markers.The role of some hormones, follicle-stimulating hormone [FSH], thyroid-stimulating hormone [TSH] and parathyroid hormone [PTH], in the development of osteoporosis in patients with endometriosis was also assessed.
American Psychological Association (APA)
al-Yasin, Firas Fadil& Tahir, Muhammad Abbas. 2015. The role of proinflammatory cytokines and some hormones in endometriosis-induced osteoporosis. Thi-Qar Medical Journal،Vol. 9, no. 1.
https://search.emarefa.net/detail/BIM-796393
Modern Language Association (MLA)
al-Yasin, Firas Fadil& Tahir, Muhammad Abbas. The role of proinflammatory cytokines and some hormones in endometriosis-induced osteoporosis. Thi-Qar Medical Journal Vol. 9, no. 1 (2015).
https://search.emarefa.net/detail/BIM-796393
American Medical Association (AMA)
al-Yasin, Firas Fadil& Tahir, Muhammad Abbas. The role of proinflammatory cytokines and some hormones in endometriosis-induced osteoporosis. Thi-Qar Medical Journal. 2015. Vol. 9, no. 1.
https://search.emarefa.net/detail/BIM-796393
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-796393