Medicinal uses of mannich bases
Joint Authors
Anwar, E. M. Nur al-Jalil
Himat, M. A. Fadl
Sad, M. H. Ayyub
Abd al-Karim, M.
Source
Sudan Medical Laboratory Journal
Issue
Vol. 3, Issue 1 (30 Jun. 2016), pp.70-74, 5 p.
Publisher
Omdurman Islamic University Faculty of Medical Laboratory
Publication Date
2016-06-30
Country of Publication
Sudan
No. of Pages
5
Main Subjects
Abstract EN
The Mannich Reaction is used in the synthesis of natural products and pharmaceuticals.
Therefore in this review we discuss the medicinal uses of Mannich bases with examples in the medicinal field.
A large number of different bioactivities of Mannich bases are anticonvulsant, antimalarial, anticancer, analgesic and antimicrobial drugs.
Also Mannich bases are used as prodrugs.
Application The Mannich reaction is one of the most important C-C bond formation methods in organic synthesis (Sharifi, et.
al , 2001).
The Mannich-reaction is employed in the organic synthesis of natural compounds like, for instance, peptides, nucleotides, antibiotics and alkaloids.
Other application are in agrochemicals such as plant growth regulators, paint and other polymer chemistry, catalysts and crosslinking and is used in the synthesis of medicinal compounds (Dimmock, 1997).
American Psychological Association (APA)
Anwar, E. M. Nur al-Jalil& Himat, M. A. Fadl& Sad, M. H. Ayyub& Abd al-Karim, M.. 2016. Medicinal uses of mannich bases. Sudan Medical Laboratory Journal،Vol. 3, no. 1, pp.70-74.
https://search.emarefa.net/detail/BIM-796464
Modern Language Association (MLA)
Anwar, E. M. Nur al-Jalil…[et al.]. Medicinal uses of mannich bases. Sudan Medical Laboratory Journal Vol. 3, no. 1 (2016), pp.70-74.
https://search.emarefa.net/detail/BIM-796464
American Medical Association (AMA)
Anwar, E. M. Nur al-Jalil& Himat, M. A. Fadl& Sad, M. H. Ayyub& Abd al-Karim, M.. Medicinal uses of mannich bases. Sudan Medical Laboratory Journal. 2016. Vol. 3, no. 1, pp.70-74.
https://search.emarefa.net/detail/BIM-796464
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 73-74
Record ID
BIM-796464