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Study of in vitro and in vivo free radical scavenging activity for radioprotection of cerium oxide nanoparticles
Other Title(s)
دراسة فعالية كسح الجذور الحرة مختبريا و الحماية الإشعاعية لجسيمات أوكسيد السيريوم النانوية
Joint Authors
Yas, Rana Muhyi
al-Mashhadani, Asya Hamid
Source
Issue
Vol. 15, Issue 35 (31 Dec. 2017), pp.40-47, 8 p.
Publisher
University of Baghdad College of Science
Publication Date
2017-12-31
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Abstract EN
Nanoceria have shown numerous unique characteristics, such as biocompatibility and are excellent agents for biological applications.
The aim of this study is to investigate cerium oxide nanoparticles for 2, 2- diphenyl-1-picryl-hydrazyl-hydrate (DPPH) free radical scavenging activity and their ability to offer protection against ionizing radiation.
In vitro antioxidant activity study of nanoceria particles has shown good free radical scavenging activity for DPPH radical assayed within a concentration range of 0.01 to 0.05 g/l, at higher concentrations of nanoparticles showed reverse trend in absorbance and inhibition indicating this finite rang of concentration is suitable for scavenging free radicals, also nanoparticles were found to have significant antioxidant capacity and thus can be used as potential radical scavenger against deleterious damages caused by the free radicals.
The results of histopathological examination showed effectiveness of CeO2 nanoparticles in radioprotection of skin cells in animal models during radiation exposure.
American Psychological Association (APA)
al-Mashhadani, Asya Hamid& Yas, Rana Muhyi. 2017. Study of in vitro and in vivo free radical scavenging activity for radioprotection of cerium oxide nanoparticles. Iraqi Journal of Physics،Vol. 15, no. 35, pp.40-47.
https://search.emarefa.net/detail/BIM-796762
Modern Language Association (MLA)
al-Mashhadani, Asya Hamid& Yas, Rana Muhyi. Study of in vitro and in vivo free radical scavenging activity for radioprotection of cerium oxide nanoparticles. Iraqi Journal of Physics Vol. 15, no. 35 (2017), pp.40-47.
https://search.emarefa.net/detail/BIM-796762
American Medical Association (AMA)
al-Mashhadani, Asya Hamid& Yas, Rana Muhyi. Study of in vitro and in vivo free radical scavenging activity for radioprotection of cerium oxide nanoparticles. Iraqi Journal of Physics. 2017. Vol. 15, no. 35, pp.40-47.
https://search.emarefa.net/detail/BIM-796762
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 46-47
Record ID
BIM-796762