Spectrum of sinonasal tumors : a 10-year experience at a Tertiary Care hospital in north India
Joint Authors
Shirazi, Nadiyah
Selvi, Thamarai N.
Harsh, Meena
Bist, Sampan S.
Source
Issue
Vol. 30, Issue 6 (31 Dec. 2015), pp.435-440, 6 p.
Publisher
Publication Date
2015-12-31
Country of Publication
Oman
No. of Pages
6
Main Subjects
Abstract EN
Objective: Sinonasal tumors are a highly heterogeneous group of tumors that account for less than 1% of all cancers.
Precise diagnosis is essential because the natural history, treatment, and prognosis vary for different neoplasms.
We reviewed 610 cases of sinonasal lesions to understand this entity better.
Methods: A total of 610 sinonasal biopsies/ specimens were received over a period of 10 years (2004–14).
All the samples were processed and stained with hematoxylin and eosin.
Special staining for microorganisms and immunohistochemistry were performed where indicated.
Results: Benign lesions were 72% with nasal polyp being the most common.
Malignant lesions made up 21.2% of lesions with nasopharyngeal carcinoma being the most common while 7.7% cases were inflammatory/non-neoplastic.
The most common cause for this was fungal sinusitis.
The maxillary sinus was the most frequently involved site in all the lesions (62%).
The average age of presentation was 40 years old, and the male to female ratio was 3:1 in those with benign tumors.
The average age of presentation in the malignant and inflammatory group were 45 and 43 years, respectively, with an almost equal sex ratio in both categories.
Computed tomography and magnetic resonance imaging scans were done in virtually all cases to assess the extent of the tumor as well as bony destruction.
Local recurrence was the most frequent cause of treatment failure.
Conclusion: Tumors of the nasal cavity are often grouped with those in the paranasal sinuses.
Benign tumors constituted approximately 75% of tumors in our hospital.
Squamous cell carcinoma was the most common malignancy of this region.
These tumors need to be studied closely and accurately because their proximity to vital structures pose significant challenges for their treatment and may be the source of significant patient morbidity.
American Psychological Association (APA)
Shirazi, Nadiyah& Bist, Sampan S.& Selvi, Thamarai N.& Harsh, Meena. 2015. Spectrum of sinonasal tumors : a 10-year experience at a Tertiary Care hospital in north India. Oman Medical Journal،Vol. 30, no. 6, pp.435-440.
https://search.emarefa.net/detail/BIM-798387
Modern Language Association (MLA)
Shirazi, Nadiyah…[et al.]. Spectrum of sinonasal tumors : a 10-year experience at a Tertiary Care hospital in north India. Oman Medical Journal Vol. 30, no. 6 (2015), pp.435-440.
https://search.emarefa.net/detail/BIM-798387
American Medical Association (AMA)
Shirazi, Nadiyah& Bist, Sampan S.& Selvi, Thamarai N.& Harsh, Meena. Spectrum of sinonasal tumors : a 10-year experience at a Tertiary Care hospital in north India. Oman Medical Journal. 2015. Vol. 30, no. 6, pp.435-440.
https://search.emarefa.net/detail/BIM-798387
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p.439-440
Record ID
BIM-798387