The valuable role of measuring serum lipid profile in cancer progression
Joint Authors
Ghahremanfard, Farahnaz
Majid, Mir Muhammad Khani
Shahnazari, Banafsheh
Gholami, Golnaz
Mahdi Zadah, Jamilah
Source
Issue
Vol. 30, Issue 5 (31 Oct. 2015), pp.353-357, 5 p.
Publisher
Publication Date
2015-10-31
Country of Publication
Oman
No. of Pages
5
Main Subjects
Abstract EN
Objective: Serum lipid levels are not only associated with etiology, but also with prognosis in cancer.
To investigate this issue further, we aimed to evaluate the serum levels of lipids in association with the most important prognostic indicators in cancer patients at the start of chemotherapy.
Methods: In a retrospective cross-sectional study, using existing medical records obtained from 2009–2014, the data of all incident cancer cases in Iranian patients referred to the Semnan oncology clinic for chemotherapy were analyzed.
Data on demographics, cancer type, prognostic indicators (e.g.
lymph node involvement, metastasis, and stage of disease), as well as the patient’s lipid profile were collected.
We used multiple logistic regression models to show the relationship between prognosis indicators and lipid profile adjusting for age, gender, and type of cancer.
Results: The data of 205 patients was gathered.
We found a significant difference in the lipid profile between different types of cancers (breast, colon, gastric, and ovarian).
With the exception of high-density lipoprotein levels in women, which were higher than in men, the means of other lipid profiles were similar between the genders.
There was a significant association between higher levels of low-density lipoprotein (LDL >110mg/dL) in the serum and metastasis (adjusted odds ratio=2.4, 95% CI 1.2–3.5).
No significant association was reported between lipid profile and lymph nodes involvement and stage of the disease.
Conclusion: Our study suggested a benefit of measuring serum levels of lipids for predicting cancer progression.
Increased LDL levels can be considered a predictive factor for increasing the risk of metastasis
American Psychological Association (APA)
Ghahremanfard, Farahnaz& Majid, Mir Muhammad Khani& Shahnazari, Banafsheh& Gholami, Golnaz& Mahdi Zadah, Jamilah. 2015. The valuable role of measuring serum lipid profile in cancer progression. Oman Medical Journal،Vol. 30, no. 5, pp.353-357.
https://search.emarefa.net/detail/BIM-799831
Modern Language Association (MLA)
Ghahremanfard, Farahnaz…[et al.]. The valuable role of measuring serum lipid profile in cancer progression. Oman Medical Journal Vol. 30, no. 5 (2015), pp.353-357.
https://search.emarefa.net/detail/BIM-799831
American Medical Association (AMA)
Ghahremanfard, Farahnaz& Majid, Mir Muhammad Khani& Shahnazari, Banafsheh& Gholami, Golnaz& Mahdi Zadah, Jamilah. The valuable role of measuring serum lipid profile in cancer progression. Oman Medical Journal. 2015. Vol. 30, no. 5, pp.353-357.
https://search.emarefa.net/detail/BIM-799831
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 357
Record ID
BIM-799831