Effects of pomegranate and spearmint syrup on nausea and vomiting during pregnancy : a randomized controlled clinical trial
Joint Authors
Sadeghpour, Omid
Mehrabani, Mitra
Abd al-Husayni, Shahrbanoo
Hashim Dabaghian, Fataneh
Mokaberinejad, Roshanak
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 19, Issue 10 (31 Oct. 2017), pp.1-7, 7 p.
Publisher
Publication Date
2017-10-31
Country of Publication
United Arab Emirates
No. of Pages
7
Main Subjects
Abstract EN
Background: Nausea and vomiting during pregnancy (NVP) affects approximately 50% - 80% of expecting mothers.
NVPcan impose negative effects on the quality of life; therefore, more attention should be paid to improve patients’ health outcomes.
Objectives: The purpose of this trial was to evaluate the efficacy of pomegranate and spearmint syrup on NVP.
Methods: In this randomized clinical trial, 74 pregnant women with moderate NVP were divided into 2 groups via block randomization method.
A total of 24 and 31 patients were analyzed in the syrup and vitamin B6 groups, respectively.
The 24-hour pregnancyunique quantification of emesis (PUQE-24) scale was used to examine the severity of NVP.
The intervention included the use of pomegranate syrup (5 cc/TDS) plus vitamin B6 in the syrup group; on the other hand, the control group only received B6 tablets (20 mg/TDS) for 1 week.
The subjects were followed-up for 1 week without any interventions.
Data were analyzed, using Chi square test for qualitative variables, t test and Mann-Whitney U test for quantitative variables, and Friedman test for repeated measures.
Results: There was no significant difference between the groups in terms of demographic and pregnancy characteristics.
The mean PUQE-24 score in the syrup group was 9.41.8 at baseline, 4.61.5 on day 7, and 4.82.6 on day 14 (P < 0.001).
The mean PUQE-24 score in the control group was 8.5 1.5 at baseline, 6 2.3 on day 7, and 6.2 2.6 on day 14 (P < 0.001).
Although a major decline in PUQE-24 scores was observed in both groups, it was more significant in the syrup group (P = 0.001).
Also, the PUQE-24 score was significantly lower in the syrup group, compared to the control group on days 7 and 14 (P = 0.02).
The visual analog scale scores also showed a greater reduction in the syrup group, compared to the control group (4.72.8 vs.
1.63; P = 0.001).
No significant difference was observed between the groups regarding the duration of nausea, frequency of vomiting, and frequency of retching; also, no complications were reported.
Conclusions: The effectiveness of pomegranate and spearmint syrup in reducing NVP was confirmed in the syrup group versus the control group with significant differences
American Psychological Association (APA)
Abd al-Husayni, Shahrbanoo& Hashim Dabaghian, Fataneh& Mokaberinejad, Roshanak& Sadeghpour, Omid& Mehrabani, Mitra. 2017. Effects of pomegranate and spearmint syrup on nausea and vomiting during pregnancy : a randomized controlled clinical trial. Iranian Red Crescent Medical Journal،Vol. 19, no. 10, pp.1-7.
https://search.emarefa.net/detail/BIM-805370
Modern Language Association (MLA)
Abd al-Husayni, Shahrbanoo…[et al.]. Effects of pomegranate and spearmint syrup on nausea and vomiting during pregnancy : a randomized controlled clinical trial. Iranian Red Crescent Medical Journal Vol. 19, no. 10 (Oct. 2017), pp.1-7.
https://search.emarefa.net/detail/BIM-805370
American Medical Association (AMA)
Abd al-Husayni, Shahrbanoo& Hashim Dabaghian, Fataneh& Mokaberinejad, Roshanak& Sadeghpour, Omid& Mehrabani, Mitra. Effects of pomegranate and spearmint syrup on nausea and vomiting during pregnancy : a randomized controlled clinical trial. Iranian Red Crescent Medical Journal. 2017. Vol. 19, no. 10, pp.1-7.
https://search.emarefa.net/detail/BIM-805370
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 7
Record ID
BIM-805370