Comparative study of vitamin (D)‎ status in full term and preterm infants and their respective mothers

Abstract EN

Background: Vitamin D is important for maintenance of calcium and phosphorus homeostasis and bone mineralization.

Vitamin D deficiency in the mothers has possible adverse effects on the fetus and contributes to low vitamin D in infancy.

Objectives: to assess vitamin D status, calcium, phosphorous and alkaline phosphate in preterm infants and their mothers.

Patients & Methods: A cross sectional study was conducted on 46 neonates, and their mothers.

The study was conducted between July and December 2013.

The following had been done for all patients.

Full medical history and Clinical examination for mothers and their neonates, Laboratory investigation.

Maternal blood and Cord blood samples were collected at Delivery to measure vitamin D (vit.

D), Calcium (Ca), phosphorus (P) and alkaline phosphates (ALP).

Results; Maternal hypovitaminosis D (vitamin D (25 (OH) D) < 10 ng mL was found in 89% of pregnant women at the time of delivery and neonatal hypovitaminosis D (vitamin D < 10 ng mL) was found in 93.5% of studied neonates.

Maternal vit D did not correlate to maternal dietary vit D, but it correlated to cord blood vit D.

Maternal vit D was correlated to cord blood vit D but not cord blood Ca, Phosphorus, or alkaline phosphatas.

Conclusion: Vitamin D levels in Egyptian mothers at delivery is deficient and it correlates well to cord blood Vitamin D levels.