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Serological markers "CEA test and sAPRIL test" in Iraqi patients with colon cancer
Joint Authors
Mahmud, Aqil Sh.
Zayni, Sarmad M. H.
Mahmud, Aqil H.
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 59, Issue 4 (31 Dec. 2017), pp.317-320, 4 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2017-12-31
Country of Publication
Iraq
No. of Pages
4
Main Subjects
Abstract EN
Background: Colonic cancer is a very common disease world-wide being fourth most common cancer characterized by abnormal proliferation of the inner wall of colon then taking full colon wall thickness then spreading to surrounding lymph nodes and tissues and finally distant metastasis.
It is one of most complicated diseases with debilitating symptoms which becomes more sever , prominent and specific with advancing stage with high percent of fatality and relatively short survival if diagnosed late or if left untreated.
Objective: To evaluate the efficacy of serum CEA & sAPRIL levels in the diagnosis and screening of colon cancer and their validity for this.
Patients and methods: This study was applied on 35 patients with colonic cancer, 35 patients with benign polyps and 15 negative controls.
All individuals were subjected to blood sampling for measuring their serum CEA & sAPRIL using ELISA technique.
Results: In this study, majority of patients with colon cancer were presented at ages between 53-82 years of age (mean 68.5±6.4 years).
Serum levels of sAPRIL & CEA were significantly elevated in those patients with advancing stages (C & D) compared with stages (A & B) and lower levels were found in patients who had surgical removal of tumor or received chemotherapy.
Also a positive relation was found between sAPRIL & CEA with alcohol intake and smoking Conclusion: according to this study sample it was found that sAPRIL and CEA together are strong indicators for colon cancer screening & diagnosis, and by this will reduce the need for more invasive screening & diagnostic tools.
Keywords: colon cancer, tumor marker, CEA, sAPRIL.
American Psychological Association (APA)
Mahmud, Aqil H.& Zayni, Sarmad M. H.& Mahmud, Aqil Sh.. 2017. Serological markers "CEA test and sAPRIL test" in Iraqi patients with colon cancer. Journal of the Faculty of Medicine Baghdad،Vol. 59, no. 4, pp.317-320.
https://search.emarefa.net/detail/BIM-809804
Modern Language Association (MLA)
Zayni, Sarmad M. H.…[et al.]. Serological markers "CEA test and sAPRIL test" in Iraqi patients with colon cancer. Journal of the Faculty of Medicine Baghdad Vol. 59, no. 4 (2017), pp.317-320.
https://search.emarefa.net/detail/BIM-809804
American Medical Association (AMA)
Mahmud, Aqil H.& Zayni, Sarmad M. H.& Mahmud, Aqil Sh.. Serological markers "CEA test and sAPRIL test" in Iraqi patients with colon cancer. Journal of the Faculty of Medicine Baghdad. 2017. Vol. 59, no. 4, pp.317-320.
https://search.emarefa.net/detail/BIM-809804
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 320
Record ID
BIM-809804