Study the relation of gastric cancer with helicobacter pylori infection among dyspeptic patients

Abstract EN

Helicobacter pylori (H.

pylori) is the main eausative agent of gastrointestinal diseases including chronic gastritis, pcptic ulcer associated disordcrs, gastric and duodcnal carcinomas Icading to morbidity and mortality in humans.

This rcsearch was conductcd to study the relation of gastric cancer with H.pylori infections through some invasivc mcthods(Histology, Direct biopsy smcar, Biopsy urcasc test and culture methods).

One hundred and twenty five dyspcptic patients were subjccted to csophagcal gastroduodenoscopy in Baghdad Teaching Hospital/ Endoscopy unit froml0/l/2013 to 8/1/2014, gastric biopsy samplcs were applicd for microbiological analysis.

The results showed that there was a rclationship between H.

pylori infection occurrence and endoscopically diagnoscd Ciastric cancer (3.2%); it was recordcd highest H.

pylori isolation (45.45%) from gastric ulcer patients followcd by (25%) from gastric cancer patients.

Histological examination recordcd that active gastritis is found to be the most infected case (93.75%) with H.

pylori followcd by gastric adenocarcinoma (66.66%) gastric lymphoma (50%), so the stu dy recordcd a signifieant association between H .py’lori infection and gastric cancer.