Antimicrobial activity of ethanolic and aqueous extracts of pomegranate peel against Extended Spectrum Beta-Lactamase producing bacteria
Other Title(s)
فعالية المستخلصات الايثانولية و المائية لقشور الرمان ضد البكتريا المنتجة لأنزيم البيتا لاكتميز الواسع الطيف
Joint Authors
Husayn, Adi Abd al-Rida
Hasan, Bassam Abd al-Husayn
Salih, Hind Abd Allah
Mutashshar, Sahar Muzhir
Abbas, Ali Tahir
Source
Issue
Vol. 12, Issue 4 (31 Dec. 2017), pp.74-87, 14 p.
Publisher
University of Thi-Qar Research and Development Department
Publication Date
2017-12-31
Country of Publication
Iraq
No. of Pages
14
Main Subjects
Topics
Abstract EN
Background: Pomegranate (Punica granatum ) is an ancient, mystical, unique fruit with potential antimicrobial activity.
Objective: This study was performed to explore the antimicrobial activity of ethanolic and aqueous extracts of pomegranate peel against extended spectrum beta-lactamase producing bacteria (Klebsiella pneumonia , Escherichia coli and Aeromonas hydrophila).
Material and Methods: 100 swabs were collected from the skin of burned patients.
The bacterial strains were identificated according to their cultural , morphological , microscopically and biochemical characteristics, then subjected to ESBL-producing screening by double-disc synergy test.
The ethanolic and aqueous extracts of pomegranate peel were prepared by using a Soxhalet apparatus and their antimicrobial activities were studied and compared with a commercial antibiotics against tested bacteria by using agar well diffusion method.
Results: Out of total 100 swabs, only three isolates produced ESBLenzyme, namely (Klebsiella pneumoniae, Escherichia coli and Aeromonas hydrophila).
Both extracts showed an effective antibacterial activity against all these bacteria.
The ethanolic extract was found to be more effective than aqueous one against all the tested microorganisms.
Conclusion: The pomegranate peel extracts have a strong antimicrobial activity against extended spectrum beta-lactamase producing bacteria.
Therefore it is an important source of new antimicrobial compounds to treat infections caused by multidrug-resistant bacterial.
American Psychological Association (APA)
Husayn, Adi Abd al-Rida& Hasan, Bassam Abd al-Husayn& Salih, Hind Abd Allah& Abbas, Ali Tahir& Mutashshar, Sahar Muzhir. 2017. Antimicrobial activity of ethanolic and aqueous extracts of pomegranate peel against Extended Spectrum Beta-Lactamase producing bacteria. University of Thi-Qar Journal،Vol. 12, no. 4, pp.74-87.
https://search.emarefa.net/detail/BIM-811057
Modern Language Association (MLA)
Husayn, Adi Abd al-Rida…[et al.]. Antimicrobial activity of ethanolic and aqueous extracts of pomegranate peel against Extended Spectrum Beta-Lactamase producing bacteria. University of Thi-Qar Journal Vol. 12, no. 4 (Dec. 2017), pp.74-87.
https://search.emarefa.net/detail/BIM-811057
American Medical Association (AMA)
Husayn, Adi Abd al-Rida& Hasan, Bassam Abd al-Husayn& Salih, Hind Abd Allah& Abbas, Ali Tahir& Mutashshar, Sahar Muzhir. Antimicrobial activity of ethanolic and aqueous extracts of pomegranate peel against Extended Spectrum Beta-Lactamase producing bacteria. University of Thi-Qar Journal. 2017. Vol. 12, no. 4, pp.74-87.
https://search.emarefa.net/detail/BIM-811057
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 83-87
Record ID
BIM-811057