Cytotoxic effect of saponins extracted from yucca on human breast cell line (HBL-100) in vitro
Joint Authors
Sajban, Liqa Hassun
al-Darraji, Mustafa Nihad Jumah
Abd al-Halim, Ansam G.
Abbud, Zaynab H.
Aftan, Ruwaydah A.
Barakat, Nadiyah Tariq
Ubayd, Hind Husayn
Source
Iraqi Journal of Biotechnology
Issue
Vol. 16, Issue 3 (30 Sep. 2017), pp.223-229, 7 p.
Publisher
University of Baghdad Genetic Engineering and Biotechnology for Postgraduate Studies
Publication Date
2017-09-30
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Abstract EN
The present study was conducted to investigate the cytotoxic effects of saponins extracted from Yucca (Yucca gloriosa var.
Variegata L) on humane breast cell line (HBL-100) on diffrcnt exposure time in vitro, by using double dilution series ( concentration between 2.44 - 5000 fig/ ml).
The results showed that the cytotoxic effect of saponins dependent on amount of dose and exposure time.
The concentration 5000 ng/ml gave higher growth inhibition (IR), were (73,78 and 96) % compared with control 100% after (24,48 and 72) hours respectively from exposure time, all inhibition rate begin decreases with decreases the concentration of saponins.
However low concentrations of extract was found to inducc the (HBL-100) cells growth and proliferation, it was between (114 to 147)% by treatment with (39.06 to 2.44) ng/ ml after 72 hours.
Yucca saponins worked in tow direction ( inhibition and proliferation), this phenomena callcd (Hormcsis).
American Psychological Association (APA)
Ubayd, Hind Husayn& Barakat, Nadiyah Tariq& Abd al-Halim, Ansam G.& Sajban, Liqa Hassun& Abbud, Zaynab H.& al-Darraji, Mustafa Nihad Jumah…[et al.]. 2017. Cytotoxic effect of saponins extracted from yucca on human breast cell line (HBL-100) in vitro. Iraqi Journal of Biotechnology،Vol. 16, no. 3, pp.223-229.
https://search.emarefa.net/detail/BIM-811281
Modern Language Association (MLA)
Abd al-Halim, Ansam G.…[et al.]. Cytotoxic effect of saponins extracted from yucca on human breast cell line (HBL-100) in vitro. Iraqi Journal of Biotechnology Vol. 16, no. 3 (2017), pp.223-229.
https://search.emarefa.net/detail/BIM-811281
American Medical Association (AMA)
Ubayd, Hind Husayn& Barakat, Nadiyah Tariq& Abd al-Halim, Ansam G.& Sajban, Liqa Hassun& Abbud, Zaynab H.& al-Darraji, Mustafa Nihad Jumah…[et al.]. Cytotoxic effect of saponins extracted from yucca on human breast cell line (HBL-100) in vitro. Iraqi Journal of Biotechnology. 2017. Vol. 16, no. 3, pp.223-229.
https://search.emarefa.net/detail/BIM-811281
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 228-229
Record ID
BIM-811281