Study the effect of dexamethasone on the external morphology features at different embryonic developmental stages in the Swiss albino mice embryos
Other Title(s)
دراسة تأثير الديكساميثازون على الخصائص المظهرية العامة لمراحل تطورية مختلفة في أجنة الفئران البيضاء
Joint Authors
al-Musawi, Sada Ghalib Tahir
Salman, Ali Naim
Source
Issue
Vol. 13, Issue 1 (31 Mar. 2018), pp.126-138, 13 p.
Publisher
University of Thi-Qar Research and Development Department
Publication Date
2018-03-31
Country of Publication
Iraq
No. of Pages
13
Main Subjects
Abstract EN
The current study was conducted for the period from September 2015 until August 2016 in college of Education for Pure Sciences - University of Thi- Qar, this study aimed to fallow the changes on the External morphology features at different Embryonic Developmental stages when the pregnant mice treated with different doses of Dexamethasone (Dex).
Use In the current study, sixty pregnant mice were randomly divided into four groups and each group of 15 pregnant mice.
Given the members of each group specific dose of Dex and at different time periods, while the control group injected with a solution of Normal Saline 0.9%, all animals received doses used by tail intravenous injection until the end of the time periods specified.
The treatment of animals under the same conditions were determined dose based on body weight, according to what is stated in the pharmaceutical constitutions.
The results of statistical analysis at the level of probability (p<0.05) to different doses Dexamethasone show there is an negative effects on mice embryo's body weights and the lengths increase with increasing of number and doses concentrations.
using of different doses of Dex showed various changes on general external morphological features and congenital malformation in embryos of treated mothers included: Death of embryos , Letter C Shape Embryos , Head hemorrhage , placenta damage , Neural Tube Defect, Trunk Torsion, curved head , Brain hypertrophy , Liver Hypertrophy , swelling , Short nostril and limbs, Convoluted Tail, Oedema ,Wrinkled skin, absent fingers and eyelids, Crooked pave, Short toes, Seal legs appearance , Tail congestion , Bulging eyes.
American Psychological Association (APA)
Salman, Ali Naim& al-Musawi, Sada Ghalib Tahir. 2018. Study the effect of dexamethasone on the external morphology features at different embryonic developmental stages in the Swiss albino mice embryos. University of Thi-Qar Journal،Vol. 13, no. 1, pp.126-138.
https://search.emarefa.net/detail/BIM-811485
Modern Language Association (MLA)
Salman, Ali Naim& al-Musawi, Sada Ghalib Tahir. Study the effect of dexamethasone on the external morphology features at different embryonic developmental stages in the Swiss albino mice embryos. University of Thi-Qar Journal Vol. 13, no. 1 (Mar. 2018), pp.126-138.
https://search.emarefa.net/detail/BIM-811485
American Medical Association (AMA)
Salman, Ali Naim& al-Musawi, Sada Ghalib Tahir. Study the effect of dexamethasone on the external morphology features at different embryonic developmental stages in the Swiss albino mice embryos. University of Thi-Qar Journal. 2018. Vol. 13, no. 1, pp.126-138.
https://search.emarefa.net/detail/BIM-811485
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 137-138
Record ID
BIM-811485