Immunophenotypic characteristics of T-acute lymphoblastic leukemia in Omani patients : a correlation with demographic factors
Joint Authors
Fawwaz, Najla
al-Mashaikhi, Azzah
al-Khatri, Zahra
al-Mamari, Sahimah
al-Khaburi, Murtada
Pathare, Anil
Source
Issue
Vol. 33, Issue 1 (31 Jan. 2018), pp.43-47, 5 p.
Publisher
Publication Date
2018-01-31
Country of Publication
Oman
No. of Pages
5
Main Subjects
Abstract EN
Objectives: To study and classify the immunophenotypic characteristics of Omani patients diagnosed with T-cell acute lymphoblastic leukemia (T-ALL) and to correlate the results with age and gender as well as biological factors (peripheral and bone marrow blast cells percentage).
Methods: Fifty cases from both genders and of all ages who fulfilled the inclusion criteria with a diagnosis of T-ALL were included in the study.
Correlation of T-ALL subtypes with age, gender, and initial bone marrow and peripheral blood blast cells percentage was assessed using ANOVA.
Results: Among the 50 T-ALL patients analyzed, 44 were male and six were female giving a male-to-female ratio of 7:1 (p = 0.007).
The average age of patients was 19.2 years with no significant differences in the three disease subtypes.
No significant association was seen between the peripheral or bone marrow blast cell percentage and the differentiation stages of the neoplastic clone of T-ALL.
All female patients were found to express an immature T-ALL phenotype.
Conclusions: This study reports the subtypes of T-ALL in Oman for the first time.
It is hoped that this will lead to a better understanding of the disease outcomes.
American Psychological Association (APA)
al-Mashaikhi, Azzah& al-Khatri, Zahra& al-Mamari, Sahimah& al-Khaburi, Murtada& Pathare, Anil& Fawwaz, Najla. 2018. Immunophenotypic characteristics of T-acute lymphoblastic leukemia in Omani patients : a correlation with demographic factors. Oman Medical Journal،Vol. 33, no. 1, pp.43-47.
https://search.emarefa.net/detail/BIM-812362
Modern Language Association (MLA)
al-Mashaikhi, Azzah…[et al.]. Immunophenotypic characteristics of T-acute lymphoblastic leukemia in Omani patients : a correlation with demographic factors. Oman Medical Journal Vol. 33, no. 1 (Jan. 2018), pp.43-47.
https://search.emarefa.net/detail/BIM-812362
American Medical Association (AMA)
al-Mashaikhi, Azzah& al-Khatri, Zahra& al-Mamari, Sahimah& al-Khaburi, Murtada& Pathare, Anil& Fawwaz, Najla. Immunophenotypic characteristics of T-acute lymphoblastic leukemia in Omani patients : a correlation with demographic factors. Oman Medical Journal. 2018. Vol. 33, no. 1, pp.43-47.
https://search.emarefa.net/detail/BIM-812362
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 47
Record ID
BIM-812362