Factors associated with post-transplant anemia among renal transplant recipients with functioning grafts in Sana’a city, Yemen
Joint Authors
Uthman, Arwa M.
Abu Asba, Najib W.
Sayf Ali, Riyad
Source
Yemeni Journal for Medical Sciences
Issue
Vol. 11, Issue 1 (31 Dec. 2017)7 p.
Publisher
University of Science and Technology
Publication Date
2017-12-31
Country of Publication
Yemen
No. of Pages
7
Main Subjects
Abstract EN
Objective: To assess the factors associated with anemia in renal transplant recipients with functioning grafts in Sana’a city, Yemen.
Methods: One hundred and thirteen adult renal transplant recipients with functioning grafts were enrolled in this study in the period from Janury to December 2014.
Biodata and clinical data were collected using a pre-designeddata collection sheet.
Hemoglobin (Hb) concentration was measured, and anemia was defined as Hb concentration less than13.0 g/dLin males and less than 12.0 g/dL in females.
The factors associated with anemia were analyzed, and independent predictors of post-transplant anemia (PTA) among renal transplant recipients were identified using a multivariable logistic regression model.
Results: PTA was detected in 23.0% of renal transplant recipients with functioning grafts.
Bivariate analysis showed a significant association of PTA with age of 50 years or older (Odds ratio (OR) = 2.7; 95% CI: 1.10–6.72; P = 0.03), history of acute rejection (OR = 3.6; 95% CI: 1.17–11.28; P = 0.019) and delayed graft function (OR = 6.2; 95% CI:1.60–24.16; P = 0.004).
Multivariable analysis using a logistic regression model identified history of acute rejection (adjusted OR = 3.9; 95% CI: 1.11–12.94; P = 0.034) and delayed graft function (adjusted OR = 4.6; 95% CI: 1.07–19.81; P = 0.04) as independent risk factors for PTA among recipients.
However, no association was found between PTA and recipient’s gender, graft source, immunosuppressive protocols, erythropoietin treatment or use of antihypertensive drugs.
Conclusions: The prevalence of PTA among Yemeni renal transplant recipients is high, with history of acute rejection and delayed graft function being the independent risk factors.
Therefore, it is recommended that physicians involved in renal transplantation consider the investigation and follow-up of transplant recipients for PTA and adopt appropriate preventive and therapeutic measures.
American Psychological Association (APA)
Uthman, Arwa M.& Abu Asba, Najib W.& Sayf Ali, Riyad. 2017. Factors associated with post-transplant anemia among renal transplant recipients with functioning grafts in Sana’a city, Yemen. Yemeni Journal for Medical Sciences،Vol. 11, no. 1.
https://search.emarefa.net/detail/BIM-813281
Modern Language Association (MLA)
Uthman, Arwa M.…[et al.]. Factors associated with post-transplant anemia among renal transplant recipients with functioning grafts in Sana’a city, Yemen. Yemeni Journal for Medical Sciences Vol. 11, no. 1 (2017).
https://search.emarefa.net/detail/BIM-813281
American Medical Association (AMA)
Uthman, Arwa M.& Abu Asba, Najib W.& Sayf Ali, Riyad. Factors associated with post-transplant anemia among renal transplant recipients with functioning grafts in Sana’a city, Yemen. Yemeni Journal for Medical Sciences. 2017. Vol. 11, no. 1.
https://search.emarefa.net/detail/BIM-813281
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references :
Record ID
BIM-813281