Efficacy of garlic and onion oils on murin experimental Cryptosporidium parvum infection

Abstract EN

The present study was done to evaluate the therapeutic effect of garlic and onion oils against experimental cryptosporidiosis in mice, Forty BALB/c mice, 3-4 weeks age have been divided into 4 groups (10 mice each), every mouse of the G1, G2, G3 were infected with C.

parvum at a dose of 103 oocyst /ml by stomach tube, G3 was positive control, while G4 was negative control.

After confirmation of infection, each mouse of G1 and G2 received 0.2 ml of garlic oil and 1 ml/100g body weight of onion oil, orally by using stomach tube daily till the end of the experiment at day 15 post treatment.

Therapeutic effect of garlic and onion oils were assessed by measuring oocyst number shedded in feces of infected groups and ileum histopathological examination at end of experiment.

The results showed that garlic oil and onion oils were effective against experimental cryotosporidiosis, garlic oil showed a more potent than onion oil (P≤0.05).

It was concluded that administration of garlic and onion oils was efficient in treating susceptible hosts against the zoonotic parasite Cryptosporidium parvum infection