Preparation and diagnosis of pyrimidines derivatives by conventional and microwave ways

Abstract EN

This work includes synthesis and characterization of new derivatives of pyrimidine (R.

or Ar.

-1, 2, 3, 4-tetrahydropyrimidin-5-yl) ethan-1-one), via the reaction of acetyl acetone with different aldehydes and guanidine hydrochloride.

Using absolute ethanol as a solvent .This mixture was refluxed for (6– 20) hrs.at pH 6 we prepared .The same derivatives of pyrimidine were prepared in microwave way.

This compounds were prepared characterized by melting point, FT-IR , UV-Vis and some of the with 1H-NMR and 13C-NMR spectroscopy .