The physiological influence of prostate size and prostatic specific antigen (PSA)‎ on the concentrations of some hormones and biochemical compounds for males in Salah Alden governorate

Abstract EN

This study was conducted to investigate the effect of differencein prostate big size benign and prostate specific antigen (PSA) concentrations on some biochemical (Glucose , Cholesterol , Acid Phosphatase) and hormones(ACTH , Estrogen , Testosterone ) in the men patients having prostatic hyperplasia and compared with healthy men.

The study was carried for 60 patients males infected by the prostatic hyperplasia and 40 healthy males, there ages were ranged between (47 – 90 years).

The results show that high significant increased (P ≤0.05) in all patients categories(20 – 40 mm3), (41 – 60) ,( 61 – and more) mm3 of prostatic with BPH in the(Glucose, Cholesterol, Acid Phosphatase ACTH and estrogen) compared with a healthy men.

There is significant (P ≤0.05) increased in the patients prostate size category of (61 – more mm3) compared with the otherpatients categories(20 – 40 mm3), (41 – 60 mm3) in the (Glucose , Acid Phosphatase , ACTH and estrogen) parameters , while the healthy men was increased significant (P ≤0.05) in the testosterone compared with all patients prostate size categories.

On the other hand the all categories for the PSA concentrations (0-3.5) , (3.6-7.0), (7.1 and more) ng/ml are increase significant (P ≤0.05) in prostatic patients compared with healthy men in the components (Glucose , Cholesterol , Acid Phosphatase ACTH) and significant increase (P ≤0.05) in healthy testosterone compared with all PSA categories of prostatic patients.

The high PSA category (7.1 and more)ng/ml gives the high concentrations in (Glucose, Cholesterol, Acid Phosphatase ACTH) and a significant effect (P ≤0.05) between the the patients categories