The cytotoxic effect of vincristine-amygdalin combi-nation on human cervical cancer cell line (Hela can-cer cell line)
Other Title(s)
التأثير السمي الخلوي لمزيج (ألامكدالين و الفنكرستيين) على خط خلايا سرطان عنق الرحم البشري Hela
Author
Source
Iraqi Journal of Cancer and Medical Genetics
Issue
Vol. 9, Issue 2 (31 Dec. 2016), pp.150-161, 12 p.
Publisher
al-Mustansyriah University Iraqi Centre for Cancer and Medical Genetics Research
Publication Date
2016-12-31
Country of Publication
Iraq
No. of Pages
12
Main Subjects
Abstract EN
Resistance of cancer cells toward chemotherapeutics drugs is considered as the major problem of cancer treatment.
One of the strategies that are used to overcome cancer cells resistance to anticancer drugs is the drugs combination.
Vincristine and amygdalin combination was used in this study to identify the possibility of synergistic effect between them as anticancer, which is mainly due to unrelated mechanism of action for vincristine and amygdalin.
The result of the study demonstrate that the cytotoxic effect of (vincristine and amygdalin) combination was significantly more than the cytotoxicity of each one alone on Hela cancer cell line (human cervical cancer cell line).
The result shows also the cytotoxicity of (vincristine and amygdalin) combination increases with the increase in the concentration which ranged between (1-10000) μg/ml, beside the increase in the incubation periods which are (24, 48 and 72) hours
American Psychological Association (APA)
Jumah, Azal Hammudi. 2016. The cytotoxic effect of vincristine-amygdalin combi-nation on human cervical cancer cell line (Hela can-cer cell line). Iraqi Journal of Cancer and Medical Genetics،Vol. 9, no. 2, pp.150-161.
https://search.emarefa.net/detail/BIM-818970
Modern Language Association (MLA)
Jumah, Azal Hammudi. The cytotoxic effect of vincristine-amygdalin combi-nation on human cervical cancer cell line (Hela can-cer cell line). Iraqi Journal of Cancer and Medical Genetics Vol. 9, no. 2 (2016), pp.150-161.
https://search.emarefa.net/detail/BIM-818970
American Medical Association (AMA)
Jumah, Azal Hammudi. The cytotoxic effect of vincristine-amygdalin combi-nation on human cervical cancer cell line (Hela can-cer cell line). Iraqi Journal of Cancer and Medical Genetics. 2016. Vol. 9, no. 2, pp.150-161.
https://search.emarefa.net/detail/BIM-818970
Data Type
Journal Articles
Language
English
Notes
Record ID
BIM-818970