Green synthesized silver nanoparticles using Cro- cus sativus L extract after reduces prehepatocellular carcinoma in rats
Other Title(s)
دقائق الفضة النانوية المخلقة خضريا باستخدام مستخلص الزعفران تحد من تكون السرطانات في الكبد الجرذان
Joint Authors
Thamir, Niran Ali
Ahmad, Basim. Sh.
al-Mashhadi, Lamya A. M.
Source
Iraqi Journal of Cancer and Medical Genetics
Issue
Vol. 9, Issue 2 (31 Dec. 2016), pp.181-186, 6 p.
Publisher
al-Mustansyriah University Iraqi Centre for Cancer and Medical Genetics Research
Publication Date
2016-12-31
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Abstract EN
In this study, the effects of green synthesized silver nanoparticles (Ag NPs) using crocus sativus L were investigated on the liver tissues of white albino rats after induced the prehepatocellular carcinoma using diethylnitrosamine.
Thirty male albino rats weight (150-200) gm ,were used by dividing them into five groups, each group contains 6 rats.
Group 1(control group) was given food and water like other groups by liberty.
Group 2 was intraperitoneal injected with single dose of diethylnitrosamine200 mg/kg b.
wt .
Group 3 was intraperitoneal injected with a AgNPs 200 mg/kg b.
wt for six weeks .
Group 4 was intraperitoneal injected with single dose of diethylnitrosamine 200 mg/kg b.
wt followed by, intraperitoneal injected with a AgNPs 200 mg/kg b.
wt for six weeks .
Group 5 was intraperitoneally injected with a AgNPs 200 mg/kg b.
wt for six weeks ,followed by intraperitoneal injected with single dose of Diethylnitrosamine200 mg/kg b.
wt .
All animals were sacrified at the end of experiment.
The histophathological studies revealed that group 1 have normal hepatocyte.
Group2 have sever necrosis, fatty change , atypical cells and bile duct proliferation .
Group 3, have normal hepatocyte cell with mild necrosis.
Groups 4, have certain area of necrosis , inflammatory cells infiltration ,congestion and mild fatty change, no atypical cells were seen.
Group 5 the liver section showing certain area of necrosis , inflammatory cells infiltration ,mild fatty change and no atypical cells.
American Psychological Association (APA)
Ahmad, Basim. Sh.& al-Mashhadi, Lamya A. M.& Thamir, Niran Ali. 2016. Green synthesized silver nanoparticles using Cro- cus sativus L extract after reduces prehepatocellular carcinoma in rats. Iraqi Journal of Cancer and Medical Genetics،Vol. 9, no. 2, pp.181-186.
https://search.emarefa.net/detail/BIM-818974
Modern Language Association (MLA)
Ahmad, Basim. Sh.…[et al.]. Green synthesized silver nanoparticles using Cro- cus sativus L extract after reduces prehepatocellular carcinoma in rats. Iraqi Journal of Cancer and Medical Genetics Vol. 9, no. 2 (2016), pp.181-186.
https://search.emarefa.net/detail/BIM-818974
American Medical Association (AMA)
Ahmad, Basim. Sh.& al-Mashhadi, Lamya A. M.& Thamir, Niran Ali. Green synthesized silver nanoparticles using Cro- cus sativus L extract after reduces prehepatocellular carcinoma in rats. Iraqi Journal of Cancer and Medical Genetics. 2016. Vol. 9, no. 2, pp.181-186.
https://search.emarefa.net/detail/BIM-818974
Data Type
Journal Articles
Language
English
Notes
Record ID
BIM-818974