Toxicopathological effects of sodium dichromate (chromium CrVI) on small intestine of laboratory albino rats (Rattus norvegicus)
Other Title(s)
التأثيرات السمية المرضية لثنائي كرومات الصوديوم في الأمعاء الدقيقة للجرذان المختبرية البيضاء
Joint Authors
Hamid, Asil Kamil
Muhammad, Zaynab Jamal
Ahmad, Jihad Abd al-Amir
Source
al-Qadisiyah Journal of Veterinary Medicine Sciences
Issue
Vol. 15, Issue 2 (31 Dec. 2016), pp.6-10, 5 p.
Publisher
al-Qadisiyah University College of Veterinary Medicine
Publication Date
2016-12-31
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Abstract EN
In order to determine the toxicopathological effects of sodium dichromate in the small intestine of laboratory albino rats, the present study performed on 30 albino rats (Rattus norvegicus) divided into five equal groups; G1 was daily administered 3 mg / 100 g.
B.W of sodium dichromate orally for 30 days.
G2 was daily administered 9 mg /100 g.
B.W of sodium dichromate orally for 30 days.
G3 was daily administered 3 mg /100 g.
B.W of sodium dichromate orally for 60 days.
G4 was daily administered 9 mg /100 g.
B.W of sodium dichromate orally for 60 days, and G5 was served as control.
The results showed mild atrophy of the intestinal villi with marked hyperplasia of goblet cells in G1, while showed moderate atrophy of intestinal villi with some areas of necrosis of enterocytes with marked infiltration of inflammatory cells in G2.
G3 showed severe atrophy in the intestinal villi with infiltration of some inflammatory cells.
G4 showed severe atrophy of intestinal villi with area of metaplasia of columnar epithelium to squamous epithelium (squamous metaplasia).
In conclusion; the sodium dichromate had major toxic effects to the epithelium of small intestine especially in highly repeated doses.
American Psychological Association (APA)
Muhammad, Zaynab Jamal& Ahmad, Jihad Abd al-Amir& Hamid, Asil Kamil. 2016. Toxicopathological effects of sodium dichromate (chromium CrVI) on small intestine of laboratory albino rats (Rattus norvegicus). al-Qadisiyah Journal of Veterinary Medicine Sciences،Vol. 15, no. 2, pp.6-10.
https://search.emarefa.net/detail/BIM-819212
Modern Language Association (MLA)
Muhammad, Zaynab Jamal…[et al.]. Toxicopathological effects of sodium dichromate (chromium CrVI) on small intestine of laboratory albino rats (Rattus norvegicus). al-Qadisiyah Journal of Veterinary Medicine Sciences Vol. 15, no. 2 (2016), pp.6-10.
https://search.emarefa.net/detail/BIM-819212
American Medical Association (AMA)
Muhammad, Zaynab Jamal& Ahmad, Jihad Abd al-Amir& Hamid, Asil Kamil. Toxicopathological effects of sodium dichromate (chromium CrVI) on small intestine of laboratory albino rats (Rattus norvegicus). al-Qadisiyah Journal of Veterinary Medicine Sciences. 2016. Vol. 15, no. 2, pp.6-10.
https://search.emarefa.net/detail/BIM-819212
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 9-10
Record ID
BIM-819212