تأثير حقن الزيلازين في الأعراض السريرية و بعض مكونات الدم الخلوية في الخيول

Abstract EN

The study aim to evaluate the effect of xylazine on the clinical signs and some cellular blood component in horses.

It was conducted on six clinically healthy Arabian horses (In Basel Al-Assad center of Arabian horses – Gerba – SYRIA), aged between 3-5 years, and weighing 250-400 kg.

The sedative drug xylazine was injected at morning before taking ration in a dose of 1mg/kg BW intravenously.

Horses were put under close observations for 24 hrs.

The heart rate, respiratory rate, body temperature, and blood samples from jugular vein in a EDTA vacutanour tubes were taken before drug injection and at 5, 15, 30, 60, 120 minutes, and 24 hrs.

after injection.

Xylazine were induce sedation and analgesia during the effect period, and cause significant decrease in respiratory rate, Hb concentration, PCV, slowing and arrhythmia of heart rate, while not cause significant changes on RBC, WBC, platelets count, and body temperature.

In conclusion, the xylazine is save sedative, and strong analgesic in a dose of 1mg/kg IV in horses, and can be used as premedication before general anesthesia without side effects.