Tinidazol solution as a new scolicidal agent in hydatid cyst surgery

Other Title(s)

استعمال محلول التندازول كقاتل لديدان الأكياس المائية جراحيا

Joint Authors

Yusuf, Amir Ayyub
Abachi, Faris Thanoon

Source

Duhok Medical Journal

Publisher

University of Duhok College of Medicine

Publication Date

2012-12-31

Country of Publication

Iraq

No. of Pages

8

Main Subjects

Medicine

English Abstract

Objectives: To evaluate the effect of Tinidazol solution as a direct injectable scolicidal agent inside the hydatid cyst.

Design: prospective Settings: Mosul University, Mosul, Iraq.

Emergency Teaching Hospital, Duhok, Iraq Subjects: Twenty volunteer patients with hydatid disease of the liver, spleen and pancreas were included in this study conducted between June 2003 and June 2011.

Intervention: The prepared Tinidazol solution was used as an intracystically injectable scolicidal agent peroperatively in quantities corresponding to the cysts’ sizes for ten minutes.

The scolices viability was established by checking the movement and activity of flame cells, disrupted membrane or stained with eosin is considered as dead.

Results: Postoperatively all subjects have good recovery, no complications, with normal serological diagnostic test effects, no sign and symptoms of cholangitis, hepatitis or recurrence within six months.

Main outcome measure: The microscopical examination by the immediate eosin staining after the Tinidazole injection revealed non-viable protoscolices.

The histopathological examination of serial sections of the cysts wall after the cysts removal, revealed laminated germinal layer of hydatid cyst and no scolices at all.

Conclusion: Tinidazol solution after its preparation can be used as a directly injectable scolicidal agent for sterilization before its removal with no evidence of any complications.

Data Type

Conference Papers

Record ID

BIM-831961

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