Gall stones: a clinico-pathological study of (275)‎ cases in Duhok City

Other Title(s)

حصى المرارة : دراسة سريرية نسجيه على 245 مريضا في مدينة دهوك

Joint Authors

Salman, Salman S.
Razzaq, Ala Hani
Ahmad, Karim Muhammad

Source

Duhok Medical Journal

Publisher

University of Duhok College of Medicine

Publication Date

2012-12-31

Country of Publication

Iraq

No. of Pages

10

Main Subjects

Medicine

English Abstract

Introduction: Gall stones disease is one of the most common problems affecting the digestive tract.

Autopsy reports have shown a prevalence of gallstone from (11%) to (35%).

The prevalence of gallstones is related to many factors, including age, gender and ethnic background.

Cholelithiasis produces diverse histopathological changes in gallbladder mucosa namely acute inflammation, chronic inflammation, glandular hyperplasia, granulomatous inflammation, cholesterolosis, dysplasia, and carcinoma.

The aims of this study were to find out the age and gender distribution of the gall stones in Duhok City, the anatomical anomalies in the biliary system and main pathologic changes in the gallbladder in association with gallstones.

Methods: This study included (275) patients; (51) males and (224) females, all of them had cholecystectomy for cholelithiasis.

The stones were analyzed chemically and the gallbladders were studied histopathologically.

Results: This study showed that females were affected more than males (4.3:1) ratio; the mostly affected age group was the fourth decade of life (30-39) years.

Mixed stones were the commonest (60.3%) followed by cholesterol stones (25%).

Anomalies of the biliary system were detected in (16) patients and include cystic duct variations (4.3%) and cystic artery variations (1.4%).

The commonest histopathological finding was chronic cholecystitis (68.3%) and malignancies constituted only (1%).

Discussion: The present work is consistent with the work of many other researchers regarding the age and gender distribution of gallstones and also regarding the effects of gallstones on the gallbladder.

But, regarding the type of stones whether cholesterol, mixed or bilirubinate stones, there are some dissimilarity with the results of some workers.

Conclusions which can be made from this study are that; gallstones are more common in women than men, the fourth decade of life is the peak incidence, the commonest pathology is chronic cholecystitis, malignancies are rare and anatomical anomalies are very important surgically

Data Type

Conference Papers

Record ID

BIM-832017

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