Protective role of some antioxidants on sperm abnormalities caused by nicotine in albino mice Mus Musculus

Other Title(s)

التأثيرات التطفيرية للنيكوتين و اختبار تأثير بعض مضادات الأكسدة (الفيتامينات)‎ في ذكور الفئران البيضاء المختبرية Mus musculus من ضرب BALB C

Joint Authors

Uthman, Galawizh O.
Ismail, Nazim J.

Source

Duhok Medical Journal

Publisher

University of Duhok College of Medicine

Publication Date

2012-12-31

Country of Publication

Iraq

No. of Pages

9

Main Subjects

Pharmacy, Health & Medical Sciences

English Abstract

To study the preventive effect of both vitamin C (Ascorbic acid) and vitamin E (a- tocopherol) on the sperm abnormalities in laboratory albino mice Mus musculus nicotine was administrated using three concentrations (10,20 and 30 µg/ mouse) through four doses daily (from 7:00 am to 7:00 pm) and for three different periods (15,30 and 45 days) while vitamin C & E were administrated half hour before and after nicotine administration with dose (100 µg/ mouse & 0.6 I.U/mouse) respectively.

The following results were observed: 1-Ability of nicotine to increase all types of qualitative sperm abnormalities in male mice significantly at (P≤ 0.01).

2- Vitamin (C) showed a strong antagonized affect against nicotine, while vitamin (E) did not show a significant effect.

Data Type

Conference Papers

Record ID

BIM-832194

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