Assessment of some hematological, biochemical parameters and cardiac biomarker levels in patients with ischemic heart disease in Erbil City

Abstract EN

The present study was designed to investigate some hematological, biochemical parameters and cardiac biomarker level in male and female patients with ischemic heart disease and healthy person.

This study was carried out in the center of heart diseases in Erbil city, one hundred twenty people participated, and sixty of them were suffering from ischemic heart disease (IHD) with both male and female sex in age range 44-72 years.

Other sixty healthy people with both sex and same age participate as a control group.

The results showed that the white blood cell (WBC)count, increased significantly(P<0.05), hemoglobin (Hb) and packed cell volume (PCV)level, red blood cell (RBC)count, mean corpuscular volume(MCV) and mean corpuscular hemoglobin(MCH) decreased significantly, mean corpuscular hemoglobin concentration(MCHC) decreased nonsignificantly, and platelet count changed nonsignificantly in male patients with IHD when compared with control group.

According to biochemical test the level of serum urea, creatinine, cholesterol, triglyceride increased significantly, low-density lipoprotein (LDL), creatine kinase (CK-MB) isoenzyme and troponin- T level increased nonsignificantly and high-density lipoprotein(HDL) level decreased significantly in male patients with IHD when compared with control group.

In female patients with IHD, the WBC count increased significantly, Hb concentration, MCV, MCH and MCHC level decreased significantly, in PCV level, RBC count and platelet count no significant changes observed when compared with control group.

There was a significant increase in serum urea, creatinine, cholesterol, triglyceride, LDL and creatine kinase(CK-MB) isoenzyme level, and a significant decrease in HDL level, while there was no significant increase in troponin- T level in female patients when compared with control group.

In conclusion, a consequence of ischemic heart disease and other risk factors, increment in white blood cells, decrement in blood cellular and alter cardiac biomarker through elevation of CK- MB isoenzyme and Troponin-T in male and female patients was observed.