A study of serum malondialdehyde and free iron levels in pregnant women

Abstract EN

The aim of the current study to find relationship between oxidative stresses that illustrated by serum iron and malondialdehyde for women during the gestation period and after delivery, comparing within the subject in healthy non-pregnant women.

The result obtained from the analysis of blood for 111 subjects aged (20 – 40) years, divided into two groups; the first group included 25 healthy subjects.

While the second group divided to four sub groups, the first trimester which included (24 subjects), the second trimester of pregnancy included (13 subjects) and the third trimester included (38 subjects) and the last fourth subgroup for those women after delivered were included (11 women).

All the chosen subjects in Erbil city.

Free serum iron level showed a slight reduce at the first trimester of pregnant (449 ± 65 μg/ dl) as compared with the normal control subjects (449.5 ± 65 μg/dl).

While in the second trimester showed a significant increase (903.31 ± 108 μg/dl) compared to the same normal value.

Also an increase of MDA concentration observed in the blood (6.527 ± 1.8 μmol/L) for the gestation women in the second trimester when compared to the normal control subjects which are (4.562 ± 0.7 μmol/L).

These results improve the relationship between free serum iron and oxidative stress in pregnant women in one hand; on the other hand, free serum iron and MDA are increasing more obvious in the second trimester of pregnancy.