In vitro biofilm formation and antimicrobial resistance pattern in Pseudomonas aeruginosa recovered from infected burn wounds in Erbil City

Abstract EN

A biofilm is a population of cells enclosed in an extracellular polysaccharides matrix, which make them grow to biotic and abiotic surfaces.

Pseudomonas aeruginosa is one of the most important biofilm-forming pathogens found to be responsible for infections on various host tissues, especially burns and surgical wounds.

Biofilm producing enables their existence in an aggressive environment of host immune system and antimicrobial agents.

The main aim of this study is to evaluate the prevalence of biofilm producers among P.

aeruginosa and to find out their antibiotic susceptibility pattern with special reference to extended-spectrum beta-lactamase (ESBLs) from patients with wound and burn infections.

All clinical isolates of P.

aeruginosa were screened for extended-spectrum beta-lactamase production and biofilm formation.

This study included 90 isolates of P.

aeruginosa from the wound and burn specimens.

About 47 out of 90 isolates were ESBLs producers, and 28 showed to be biofilm-forming pathogens.

In conclusion the biofilm producing pathogenic P.

aeruginosa showed high resistance rate to almost all the frequently used antibiotics.

Prominently extended-spectrum beta-lactamase phenotype was not strongly associated with biofilm formation in P.

aeruginosa