Molecular characterization of cutaneous leishmaniasis isolated from human in Erbil Province-Kurdistan Region Iraq
Author
Source
ZANCO Journal of Pure and Applied Sciences
Issue
Vol. 30, Issue 2 (30 Apr. 2018), pp.76-85, 10 p.
Publisher
Salahaddin University-Erbil Department of Scientific Publications
Publication Date
2018-04-30
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Pharmacy, Health & Medical Sciences
Medicine
Topics
Abstract EN
Cutaneous leishmaniasis (CL) is a parasitic disease of public health problem in Erbil Province, Kurdistan Region/ Iraq.
The identification of the parasite species causing these diseases is a pre-requisite for understanding disease epidemiology.
In the current study a higher rate of infection was found in males than females (60.34% versus 39.66%).
Most lesions were found on upper limbs (41.38%), while lower rates were found in the legs (24.14%).
Regarding age, the highest rate (27.59%) of infections was observed in the age group 1-9 years, while the lowest rate infections (13.79%) were observed in the age group over 40years.
Regarding the residency, the overall rate of CL in the inhabitants of the rural area was higher as compared to that of urban inhabitants.
The polymerase chain reaction products were sequenced and further examined by sequence analysis, 33 isolates, independent of the host, exhibited L.
tropica while in 15 samples, Nucleotide substitution generate polymorphism at position 132 nucleotide (C-G), Furthermore, ten human samples have more than one nucleotide substitution (G to T) at positions 246 and 276 and G to A at position 281.
The sequencing of the PCR products recognized 3 haplotypes, which are not described in Kurdistan Region and Iraq.
Thus, monitoring of CL and sustained surveillance system is crucial in counteracting the disease, and if possible, to control it.
American Psychological Association (APA)
Hasan, Zubayr Ismail. 2018. Molecular characterization of cutaneous leishmaniasis isolated from human in Erbil Province-Kurdistan Region Iraq. ZANCO Journal of Pure and Applied Sciences،Vol. 30, no. 2, pp.76-85.
https://search.emarefa.net/detail/BIM-832263
Modern Language Association (MLA)
Hasan, Zubayr Ismail. Molecular characterization of cutaneous leishmaniasis isolated from human in Erbil Province-Kurdistan Region Iraq. ZANCO Journal of Pure and Applied Sciences Vol. 30, no. 2 (2018), pp.76-85.
https://search.emarefa.net/detail/BIM-832263
American Medical Association (AMA)
Hasan, Zubayr Ismail. Molecular characterization of cutaneous leishmaniasis isolated from human in Erbil Province-Kurdistan Region Iraq. ZANCO Journal of Pure and Applied Sciences. 2018. Vol. 30, no. 2, pp.76-85.
https://search.emarefa.net/detail/BIM-832263
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 82-85
Record ID
BIM-832263