Study of serum magnesium and calcium in preeclampsia and normal pregnancy

Other Title(s)

دراسة مستويات المغنيسيوم و الكالسيوم في الدم بين النساء الحوامل الأصحاء و الحوامل قبل تسمم الحمل

Author

Garabit, Sinan Butrus

Source

Duhok Medical Journal

Publisher

University of Duhok College of Medicine

Publication Date

2012-12-31

Country of Publication

Iraq

No. of Pages

7

Main Subjects

Pharmacy, Health & Medical Sciences

English Abstract

Background and objectives: The cause of pre-eclampsia remains unknown; calcium and magnesium have been blamed to play a role in its pathtogensis.

The objective of this study was to assess variations in serum levels of those cations in healthy pregnant women and those with pre-eclampsia.

Methods:This prospective study evaluated the serum levels of magnesium and calcium in the second half of pregnancy in 30 healthy normotensive pregnant women, 30 pre-eclamptic cases, thirty five age - matched healthy non-pregnant women served as a control.

The study was conducted in the period of July 2010 - May 2011 Results: Pre-eclamptic women had a significant decrease in mean serum magnesium concentration (1.53 ± 0.65 mg/dL) compared with the healthy normotensive pregnant women (2.26 ± 0.73 mg/dL) and the healthy nonpregnant controls (2.31± 0.29 mg/dL).

Pre-eclamptic women had a decrease in mean serum calcium concentration (8.72±0.59 mg/dL) compared with the healthy normotensive pregnant women (8.97 ± 0.52 mg/dL) and the healthy non-pregnant controls (9.12 ± 0.31 mg/dL) but these differences were not significant.

Conclusion: Pre-eclampsia was clearly associated with significant hypomagnesaemia.

This association may be significant in understanding the pathophysiological processes of pre-eclampsia.

However, the association was not so clear for serum calcium.

Data Type

Conference Papers

Record ID

BIM-832289

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