Immune profile in aborted Iraqi women with toxoplasmosis
Joint Authors
al-Mayah, Qasim Sharhan
Hashim, Sadiq Kadhin
Qassim, Khalid Walid
Hasan, Jabir Salman
al-Dabbagh, Muhammad Abd al-Jabbar Hammudi
Sallum, Dunya Farid
Source
Issue
Vol. 15, Issue 1 (31 Mar. 2018), pp.48-52, 5 p.
Publisher
University of Babylon College of Medicine
Publication Date
2018-03-31
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Abstract EN
Background : Toxoplasmosis is one of the most important causes for abortion in women.
The immune responses have a role in the outcome of such infection in gestated women.
Aim : The current study was designed to investigate the immune profile in aborted Iraqi women with toxoplasmosis.
Materials and Methods : Fifty-five aborted women and 29 healthy control women were enrolled in this study.
Enzyme-linked immunosorbent assays were used to estimate serum levels to each of interleukin-1 alpha (IL-1α), granulocyte-monocyte colony-stimulating factor, IL-8, IL-4 IL-10, IL-12, interferon gamma (INF-ɣ), and IL-6.
Single-radial-immunodiffusion assay was used to estimate serum levels of C3, C4, and total immunoglobulin gamma.
Results : Serum levels of IL-8 showed significant elevation, while IL-6 and INF-ɣ showed significant dropping in infected women compared to control.
Other immune factors showed nonsignificant differences between the two groups of the present study.
Conclusion : Disturbance of immune response associated with toxoplasmosis may explain the success of parasite in escaping from discrimination and elimination by the immune system then supporting its survival and replication.
American Psychological Association (APA)
al-Dabbagh, Muhammad Abd al-Jabbar Hammudi& Hashim, Sadiq Kadhin& Qassim, Khalid Walid& al-Mayah, Qasim Sharhan& Hasan, Jabir Salman& Sallum, Dunya Farid. 2018. Immune profile in aborted Iraqi women with toxoplasmosis. Medical Journal of Babylon،Vol. 15, no. 1, pp.48-52.
https://search.emarefa.net/detail/BIM-832474
Modern Language Association (MLA)
al-Dabbagh, Muhammad Abd al-Jabbar Hammudi…[et al.]. Immune profile in aborted Iraqi women with toxoplasmosis. Medical Journal of Babylon Vol. 15, no. 1 (Jan. / Mar. 2018), pp.48-52.
https://search.emarefa.net/detail/BIM-832474
American Medical Association (AMA)
al-Dabbagh, Muhammad Abd al-Jabbar Hammudi& Hashim, Sadiq Kadhin& Qassim, Khalid Walid& al-Mayah, Qasim Sharhan& Hasan, Jabir Salman& Sallum, Dunya Farid. Immune profile in aborted Iraqi women with toxoplasmosis. Medical Journal of Babylon. 2018. Vol. 15, no. 1, pp.48-52.
https://search.emarefa.net/detail/BIM-832474
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 51-52
Record ID
BIM-832474