Indirect spectrophotometric methods for the determination of cefadroxil in its pure and pharmaceutical preparations
Other Title(s)
طرائق طيفية غير مباشرة لتقدير السيفادروكسيل الحر و في مستحضراته الصيدلانية
Joint Authors
Sihri, Muhannad M.
Ome, Shilan A.
Uthman, Nabil S.
Source
Issue
Vol. 26, Issue 1 (31 Dec. 2017), pp.56-65, 10 p.
Publisher
University of Mosul College of Science
Publication Date
2017-12-31
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Abstract EN
Two spectrophotometric methods were described for the determination of cefadroxil in pure form and in its pharmaceutical preparations.
They were based on the oxidation-reduction reaction between iron (III) and cefadroxil, the liberated Fe+2 is then reacted with 1, 10-phenathroline (method I) or 2, 2`-bipyridyl (method II) in acidic medium, the colored(red) complexes absorbed at 510 and 521 nm, respectively.
Applying the optimum working conditions, cefadroxil can be determined over the concentration range of 0.5-5 and 0.5-6 μg.ml-1 with molar absorptivities of 1.141 x 105 and 6.308×104 l.
mol-1 .cm-1 for method I and method II, respectively.
The proposed methods were applied successfully to the determination of cefadroxil in various pharmaceutical preparations.
American Psychological Association (APA)
Uthman, Nabil S.& Sihri, Muhannad M.& Ome, Shilan A.. 2017. Indirect spectrophotometric methods for the determination of cefadroxil in its pure and pharmaceutical preparations. Rafidain Journal of Science،Vol. 26, no. 1, pp.56-65.
https://search.emarefa.net/detail/BIM-833716
Modern Language Association (MLA)
Uthman, Nabil S.…[et al.]. Indirect spectrophotometric methods for the determination of cefadroxil in its pure and pharmaceutical preparations. Rafidain Journal of Science Vol. 26, no. 1 (2017), pp.56-65.
https://search.emarefa.net/detail/BIM-833716
American Medical Association (AMA)
Uthman, Nabil S.& Sihri, Muhannad M.& Ome, Shilan A.. Indirect spectrophotometric methods for the determination of cefadroxil in its pure and pharmaceutical preparations. Rafidain Journal of Science. 2017. Vol. 26, no. 1, pp.56-65.
https://search.emarefa.net/detail/BIM-833716
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 64-65
Record ID
BIM-833716