The clinical significance of acute phase proteins and biochemical changes in sheep with acute ruminal acidosis
Other Title(s)
الدلالات الإكلينيكية للبروتينات الحادة و التغيرات البيو كيميائية في الأغنام ذات حموضة الكرش الحادة
Joint Authors
Qamar, Ahmad Muhammad
Hasan, Hani Yusuf
Ali, Mahmud Allam
Nayil, Muhammad Abu al-Izz
al-Sayfi, Ahmad Mahmud
Salamah, Akram Ahmad
Source
Kufa Journal for Veterinary Medical Sciences
Issue
Vol. 8, Issue 2 (31 Dec. 2017), pp.221-230, 10 p.
Publisher
University of Kufa Faculty of Veterinary Medicine
Publication Date
2017-12-31
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Abstract EN
Acute ruminal acidosis is a common problem in ruminants that feed on high amount of concentrates and has been associated with inflammatory condition of the rumen and metabolic acidosis.
The goals of this study were to measure the acute phase proteins (haptoglobin and Creactive protein concentrations), and biochemical changes and to determine their association with the inflammatory condition and mortality in sheep with acute ruminal acidosis.
A total of 25 sheep were included in this study and divided in to two groups [one group suffered from acute ruminal acidosis (n=15) and another control healthy group (n=10)].
Haptoglobin and C- reactive protein (CRP) concentrations were measured by turbidimetric immunoassays.
While biochemical parameters were measured using spectrophotometric calorimetric methods.
Haptoglobin concentrations were significantly higher in sheep with acute ruminal acidosis compared to control group (P < 0.05).
However, CRP were not statistically different between both group of sheep (P > 0.05) Moreover, serum haptoglobin concentrations were higher in non-survivors sheep with acute ruminal acidosis compared to survivors (P < 0.05).
The likelihood of mortality was associated with elevated serum haptoglobin, lactate and potassium but also associated with low calcium and chloride concentrations in sheep with acute ruminal acidosis (P < 0.05).
In conclusion, haptoglobin concentrations were elevated in sheep with acute ruminal acidosis and could be considered more diagnostic and sensitive inflammatory biomarker than CRP in sheep with acute ruminal acidosis.
Alterations of biochemical dynamics including lactate, electrolytes and minerals concentrations and energy metabolism could be involved in increased risk of nonsurvival in sheep with acute lactic acidosis.
American Psychological Association (APA)
Qamar, Ahmad Muhammad& Hasan, Hani Yusuf& Ali, Mahmud Allam& Nayil, Muhammad Abu al-Izz& al-Sayfi, Ahmad Mahmud& Salamah, Akram Ahmad. 2017. The clinical significance of acute phase proteins and biochemical changes in sheep with acute ruminal acidosis. Kufa Journal for Veterinary Medical Sciences،Vol. 8, no. 2, pp.221-230.
https://search.emarefa.net/detail/BIM-833964
Modern Language Association (MLA)
Qamar, Ahmad Muhammad…[et al.]. The clinical significance of acute phase proteins and biochemical changes in sheep with acute ruminal acidosis. Kufa Journal for Veterinary Medical Sciences Vol. 8, no. 2 (Dec. 2017), pp.221-230.
https://search.emarefa.net/detail/BIM-833964
American Medical Association (AMA)
Qamar, Ahmad Muhammad& Hasan, Hani Yusuf& Ali, Mahmud Allam& Nayil, Muhammad Abu al-Izz& al-Sayfi, Ahmad Mahmud& Salamah, Akram Ahmad. The clinical significance of acute phase proteins and biochemical changes in sheep with acute ruminal acidosis. Kufa Journal for Veterinary Medical Sciences. 2017. Vol. 8, no. 2, pp.221-230.
https://search.emarefa.net/detail/BIM-833964
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 228-230
Record ID
BIM-833964