Isolation, purification and identification of active chemical compound lup-20 (29)-ene-3, 28-diol (betulin) from tetradium daniellii leaves and study the hypoglycemic effect on rabbits
Other Title(s)
عزل، تنقية و تشخيص المركب الكيميائي الفعال Lup-20(29)-ene-3, 28-diol من أوراق نبات Tetradium daniellii و دراسة تأثيره المخفض لسكر الدم في الأرانب المختبرية
Author
Source
Issue
Vol. 6, Issue 1 (31 Dec. 2016), pp.54-61, 8 p.
Publisher
University of Thi-Qar College of Science
Publication Date
2016-12-31
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Abstract EN
Diabetes mellitus is a syndrome and serious complex chronic condition leading to higher blood glucose levels that is a major source of health disorder worldwide, about 171 million or more diabetes mellitus cases worldwide in patients ages 20 years or more.
The active chemicals compounds that isolated from medicinal plants were used succifully to treat this disease .the current study was extracted and isolated the bioactive compound (Lup-20(29)-ene-3, 28- diol ) from (Tetradium daniellii ) leaves.
Were isolated, separated, purified and identified by thin layer chromatography, column chromatography, gas chromatography, IR-spectroscopy, 1H-NMR,C13-NMR,dept-NMR, Gas chromatography – mass spectroscopy.
Also study of hypoglycemic action in blood glucose levels in normalglycemic and alloxan induced diabetic rabbits of Lup-20(29)-ene-3, 28-diol compound, a significant decreasing (P<0.01) at fourth and sixth hrs , and high significant decreasing (P<0.001) at twenty forth hrs.
in hyperglycemic rabbits ,while in no rmalglycaemic rabbits, a significant decline (P<0.05) was at sixth , and a high significant decreasing ( P<0.01) was recorded at twenty forth hrs.
American Psychological Association (APA)
al-Sadi, Jamal Harbi Husayn. 2016. Isolation, purification and identification of active chemical compound lup-20 (29)-ene-3, 28-diol (betulin) from tetradium daniellii leaves and study the hypoglycemic effect on rabbits. Journal of Thi-Qar Science،Vol. 6, no. 1, pp.54-61.
https://search.emarefa.net/detail/BIM-834084
Modern Language Association (MLA)
al-Sadi, Jamal Harbi Husayn. Isolation, purification and identification of active chemical compound lup-20 (29)-ene-3, 28-diol (betulin) from tetradium daniellii leaves and study the hypoglycemic effect on rabbits. Journal of Thi-Qar Science Vol. 6, no. 1 (Dec. 2016), pp.54-61.
https://search.emarefa.net/detail/BIM-834084
American Medical Association (AMA)
al-Sadi, Jamal Harbi Husayn. Isolation, purification and identification of active chemical compound lup-20 (29)-ene-3, 28-diol (betulin) from tetradium daniellii leaves and study the hypoglycemic effect on rabbits. Journal of Thi-Qar Science. 2016. Vol. 6, no. 1, pp.54-61.
https://search.emarefa.net/detail/BIM-834084
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 60-61
Record ID
BIM-834084