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Synthesis and identification of some Benzoxazole derivatives via Mannich reaction
Other Title(s)
تحضير و تشخيص بعض مشتقات البنزوكسازول باستخدام تفاعل مانخ
Author
Source
Issue
Vol. 25, Issue 3 (31 Dec. 2014), pp.50-55, 6 p.
Publisher
University of Mosul College of Science
Publication Date
2014-12-31
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Abstract EN
The p-Hydroxybenzyldehyde is one of the aromatic compounds which contains two important functional groups (OH, CHO).
In this work, the p-hydroxybenzyldehyde has been introduced into different reactions.
The first one involves the synthesis of ether via Williamson reaction, in which p-hydroxybenzyldehyd reacts with chloroacetic acid to afford compound (1), then compound (1) in presence of sodium bicarbonate gives the anion (2).
Which reacts with propargyl bromide to give the acetylenic compound (3).
The compound (3) in turn reacts with secondary amine via Mannich reaction to give the acetylenic amines(4a-f).
Finally, the compounds (4a-f) undergo reaction with o-amino phenol to give benzoxazole derivatives (5a-f).
The structure of synthesized compounds had been elucidated by the available physical and spectral data.
American Psychological Association (APA)
Sultan, Asma H.. 2014. Synthesis and identification of some Benzoxazole derivatives via Mannich reaction. Rafidain Journal of Science،Vol. 25, no. 3, pp.50-55.
https://search.emarefa.net/detail/BIM-834195
Modern Language Association (MLA)
Sultan, Asma H.. Synthesis and identification of some Benzoxazole derivatives via Mannich reaction. Rafidain Journal of Science Vol. 25, no. 3 (2014), pp.50-55.
https://search.emarefa.net/detail/BIM-834195
American Medical Association (AMA)
Sultan, Asma H.. Synthesis and identification of some Benzoxazole derivatives via Mannich reaction. Rafidain Journal of Science. 2014. Vol. 25, no. 3, pp.50-55.
https://search.emarefa.net/detail/BIM-834195
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 50-55
Record ID
BIM-834195