Preparation, characterization and biological study of new derivatives of 1, 3, 4-thiadiazoleand its complexes with some transitional element Ions
Joint Authors
Flife, Ibrahim A.
al-Kafiji, Abd al-Sadah Naim
Source
Issue
Vol. 6, Issue 3 (31 Dec. 2017), pp.90-100, 11 p.
Publisher
University of Thi-Qar College of Science
Publication Date
2017-12-31
Country of Publication
Iraq
No. of Pages
11
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
The current study involved preparation of ligand [2,5-bis-(2-(diphenyl methylene) hydrazineyl)-1,3,4-thiadiazole] (L1) from reacting between thiadiazole derivative [ (2,5-dihydrazineyl-1,3,4 -thiadiazol) and Benzphenone by the ratio (1:2) .
Attended the transitional elements ions complexes [Cr+3, Fe+3, Co+3, Ni+2, Cu+2] with ligand (L1) Complexes were diagnosed using the precision analysis of elements (C.H.N), Infrared spectrum (FTIR), Spectrum of Nuclear Magnetic Resonance proton (1H-NMR), Mass spectroscopy, measurement magnetic sensitivity and measurement molar conductivity the results were practical exactly matching with the molecular and structural formulas of the proposed compound .Hyperchem was used to draw ligand (L1) and its complexes and to show the distribution of electronic density.
Data obtained indicates that the stereochemistry figure of the complexes [Cr+3, Fe+3, Co+3] was octahedral , the proposed stereochemistry figure of the complexes [Ni+2, Cu+2] is square planer.
A study was conducted testing the biological activity for the prepared ligand (L1) and its complexes against two types of bacteria staphylococcus aureus and Escherichia coli compared to the standard inhibitor (Cipro.), the results obtained confirmed that ligand(L1) and their complexes did not show any biological activity towards the bacteria aureus staphylococcus aureus, while the ligand(L1) and their complexes showed different activity twards the second type of bacteria Escherichia coli, some showed greater activity than the standard inhibitor and some showed less activity than the standard inhibitor.
American Psychological Association (APA)
Flife, Ibrahim A.& al-Kafiji, Abd al-Sadah Naim. 2017. Preparation, characterization and biological study of new derivatives of 1, 3, 4-thiadiazoleand its complexes with some transitional element Ions. Journal of Thi-Qar Science،Vol. 6, no. 3, pp.90-100.
https://search.emarefa.net/detail/BIM-834333
Modern Language Association (MLA)
Flife, Ibrahim A.& al-Kafiji, Abd al-Sadah Naim. Preparation, characterization and biological study of new derivatives of 1, 3, 4-thiadiazoleand its complexes with some transitional element Ions. Journal of Thi-Qar Science Vol. 6, no. 3 (Dec. 2017), pp.90-100.
https://search.emarefa.net/detail/BIM-834333
American Medical Association (AMA)
Flife, Ibrahim A.& al-Kafiji, Abd al-Sadah Naim. Preparation, characterization and biological study of new derivatives of 1, 3, 4-thiadiazoleand its complexes with some transitional element Ions. Journal of Thi-Qar Science. 2017. Vol. 6, no. 3, pp.90-100.
https://search.emarefa.net/detail/BIM-834333
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 98-100
Record ID
BIM-834333