The relationship between cytokines and toxoplasma infection in heart disease patients
Other Title(s)
دراسة الارتباط بين بعض السيتوكينات و داء المقوسات في مرضى القلب
Joint Authors
al-Abbudi, Bsuad Aqrab Muallah
Muhammad, Ahmad Hasan
Abd al-Husayn, Haydar Sabah
Source
Issue
Vol. 6, Issue 2 (30 Jun. 2017), pp.27-32, 6 p.
Publisher
University of Thi-Qar College of Science
Publication Date
2017-06-30
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Pharmacy, Health & Medical Sciences
Topics
Abstract EN
Toxoplasmosis is the general term for infection and disease in man and animal caused by a parasite called Toxoplasma gondii, this disease is prevalent among different categories of people, Heart disease are one of them.
Because of the dormancy status of T.
gondii, there is ambiguity and variation in the immunity of patients.
This study aimed to investigate the immune status of heart disease patients infected with toxoplasmosis.
Two hundred and fifty samples of both heart disease patients and controls had been tested by ELISA technique to detect anti-Toxoplasma Abs (IgG and IgM).
The positive samples with toxoplasmosis were tested to detect the level of interleukins (IL-10, IL-12 and IL-17).
The result of this study revealed the prevalence of toxoplasmosis among heart disease patient in about (43.33% IgG and 0.66% IgM).
The results of interleukins appeared high level of IL-12 (82.85 pg./ml) in heart disease patients infected with toxoplasmosis when compared with control (60.97 pg./ml) with significant difference between them at p≤0.05, while there was no significant difference in IL-10 between patients and controls.
The results also showed decreased level of IL-17 in patients with heart disease.
The increased level of IL-12 in patient with heart disease infected with toxoplasmosis indicate to the activity of cell mediated immunity in those patients and may be lead to provoke an inflammatory status in the heart valves and muscle then worse heart disease to be sever and need complicated treatments.
American Psychological Association (APA)
Abd al-Husayn, Haydar Sabah& al-Abbudi, Bsuad Aqrab Muallah& Muhammad, Ahmad Hasan. 2017. The relationship between cytokines and toxoplasma infection in heart disease patients. Journal of Thi-Qar Science،Vol. 6, no. 2, pp.27-32.
https://search.emarefa.net/detail/BIM-834595
Modern Language Association (MLA)
Abd al-Husayn, Haydar Sabah…[et al.]. The relationship between cytokines and toxoplasma infection in heart disease patients. Journal of Thi-Qar Science Vol. 6, no. 2 (Jun. 2017), pp.27-32.
https://search.emarefa.net/detail/BIM-834595
American Medical Association (AMA)
Abd al-Husayn, Haydar Sabah& al-Abbudi, Bsuad Aqrab Muallah& Muhammad, Ahmad Hasan. The relationship between cytokines and toxoplasma infection in heart disease patients. Journal of Thi-Qar Science. 2017. Vol. 6, no. 2, pp.27-32.
https://search.emarefa.net/detail/BIM-834595
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 31-32
Record ID
BIM-834595