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Insights of antidiabetic, anti-inflammatory and hepatoprotective properties of antimicrobial secondary metabolites of corm extract from caladium x hortulanum
Joint Authors
Vijayaraghavan, Ponnuswamy
Shazhni, J. R. Abima
Renu, A.
Source
Saudi Journal of Biological Sciences
Issue
Vol. 25, Issue 8 (31 Dec. 2018), pp.1755-1761, 7 p.
Publisher
Publication Date
2018-12-31
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Topics
Abstract EN
Medicinal plants have therapeutic potential and are used worldwide to treat various diseases.
In this study, the corm of Caladium x hortulanum was extracted with various solvents and implied the availability of phytochemicals such as flavonoids, alkaloids, tannins, steroids, phenols, glycosides, saponins and terpenoids.
The solvent extracts of the corm showed antibacterial and antifungal activity with the growth inhibition zone ranged 0–24 mm.
The isolation of phytochemicals was carried out using gel column chromatography, Thin Layer Chromatography followed by High Performance Liquid Chromatography.
Gas Chromatography and Mass Spectrophotometry analysis was used to determine the phytochemicals.
The corm extract showed potent antidiabetic activity on Hep G2 cell lines and CCl4 induced toxicity was elucidated.
This possessed antiinflammatory property on murine monocyclic macrophage cell line RAW 264.7 showed 45.85 ± 1.8% inhibition of cyclooxygenase activity.
The corm extract showed hepatoprotective activity.
The CCl4 incorporated Hep G2 cells showed 19.629 ± 1.5% viability, whereas viability increased as 78.82 ± 1.9% at 100 mg/ml of extract.
American Psychological Association (APA)
Shazhni, J. R. Abima& Renu, A.& Vijayaraghavan, Ponnuswamy. 2018. Insights of antidiabetic, anti-inflammatory and hepatoprotective properties of antimicrobial secondary metabolites of corm extract from caladium x hortulanum. Saudi Journal of Biological Sciences،Vol. 25, no. 8, pp.1755-1761.
https://search.emarefa.net/detail/BIM-835305
Modern Language Association (MLA)
Shazhni, J. R. Abima…[et al.]. Insights of antidiabetic, anti-inflammatory and hepatoprotective properties of antimicrobial secondary metabolites of corm extract from caladium x hortulanum. Saudi Journal of Biological Sciences Vol. 25, no. 8 (Dec. 2018), pp.1755-1761.
https://search.emarefa.net/detail/BIM-835305
American Medical Association (AMA)
Shazhni, J. R. Abima& Renu, A.& Vijayaraghavan, Ponnuswamy. Insights of antidiabetic, anti-inflammatory and hepatoprotective properties of antimicrobial secondary metabolites of corm extract from caladium x hortulanum. Saudi Journal of Biological Sciences. 2018. Vol. 25, no. 8, pp.1755-1761.
https://search.emarefa.net/detail/BIM-835305
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1760-1761
Record ID
BIM-835305