Rapidly progressive glomerulonephritis : a wild card manifestation of lupus nephritis
Author
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 29, Issue 2 (30 Apr. 2018), pp.443-451, 9 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2018-04-30
Country of Publication
Saudi Arabia
No. of Pages
9
Main Subjects
Abstract EN
A significant proportion of individuals with systemic lupus erythematosus (SLE) will have clinical or laboratory evidence of renal involvement at some point in the course of their disease.
Lupus nephritis (LN) is one of the more important systemic manifestations of SLE and although progression to end-stage renal disease (ESRD) is not usually the norm, a significant minority of patients will do so, some in a rather dramatic fashion.
It is in such instances that LN constitutes a true nephrologic emergency.
Gratifyingly, it is rarely a silent emergency and heightened awareness amongst clinicians about its unpredictable course should lead to earlier recognition and intervention.
For this reason, a case of LN presenting with historical and histologic evidence of chronic kidney disease and superimposed, acute acceleration of renal function decline, leading rapidly to ESRD is reported here.
A brief review of the literature surrounding the pathophysiologic mechanisms, clinicopathologic characteristics and current therapeutic approaches to LN is subsequently explored.
American Psychological Association (APA)
Komolafe, Opeyemi O.. 2018. Rapidly progressive glomerulonephritis : a wild card manifestation of lupus nephritis. Saudi Journal of Kidney Diseases and Transplantation،Vol. 29, no. 2, pp.443-451.
https://search.emarefa.net/detail/BIM-838542
Modern Language Association (MLA)
Komolafe, Opeyemi O.. Rapidly progressive glomerulonephritis : a wild card manifestation of lupus nephritis. Saudi Journal of Kidney Diseases and Transplantation Vol. 29, no. 2 (Mar. / Apr. 2018), pp.443-451.
https://search.emarefa.net/detail/BIM-838542
American Medical Association (AMA)
Komolafe, Opeyemi O.. Rapidly progressive glomerulonephritis : a wild card manifestation of lupus nephritis. Saudi Journal of Kidney Diseases and Transplantation. 2018. Vol. 29, no. 2, pp.443-451.
https://search.emarefa.net/detail/BIM-838542
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 449-451
Record ID
BIM-838542