Unusual cause of crystalline nephropathy
Joint Authors
Murugesan, V.
Gopalakrishnan, Natarajan
Dineshkumar, Thanigachalam
Sakthirajan, Ramanathan
Balasubramaniyan, T.
Dhanapriya, Jeyachandran
Rajasekar, Dhanasekaran
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 29, Issue 2 (30 Apr. 2018), pp.462-465, 4 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2018-04-30
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Abstract EN
Adenine phosphoribosyltransferase deficiency is a rare, inherited autosomal recessive disease presenting with 2,8-dihydroxyadenine (DHA) urolithiasis, DHA nephropathy, and chronic kidney disease.
The presence of DHA crystals in urine and renal biopsy is pathognomonic of the disease.
We report a 23-year-old female with acute renal failure and nephrotic proteinuria.
Urinalysis showed reddish brown, round crystals with dark outline, and central spicules consistent with 2,8-DHA crystals.
Renal biopsy showed membranous nephropathy and 2,8-DHA nephropathy.
Our patient improved with liberal fluid intake, restriction of high adenine content foods, and oral xanthine dehydrogenase inhibitor febuxostat.
Early diagnosis and initiation of treatment prevent renal complications
American Psychological Association (APA)
Gopalakrishnan, Natarajan& Rajasekar, Dhanasekaran& Dhanapriya, Jeyachandran& Dineshkumar, Thanigachalam& Sakthirajan, Ramanathan& Balasubramaniyan, T.…[et al.]. 2018. Unusual cause of crystalline nephropathy. Saudi Journal of Kidney Diseases and Transplantation،Vol. 29, no. 2, pp.462-465.
https://search.emarefa.net/detail/BIM-838545
Modern Language Association (MLA)
Gopalakrishnan, Natarajan…[et al.]. Unusual cause of crystalline nephropathy. Saudi Journal of Kidney Diseases and Transplantation Vol. 29, no. 2 (Mar. / Apr. 2018), pp.462-465.
https://search.emarefa.net/detail/BIM-838545
American Medical Association (AMA)
Gopalakrishnan, Natarajan& Rajasekar, Dhanasekaran& Dhanapriya, Jeyachandran& Dineshkumar, Thanigachalam& Sakthirajan, Ramanathan& Balasubramaniyan, T.…[et al.]. Unusual cause of crystalline nephropathy. Saudi Journal of Kidney Diseases and Transplantation. 2018. Vol. 29, no. 2, pp.462-465.
https://search.emarefa.net/detail/BIM-838545
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 465
Record ID
BIM-838545