A rare concurrence of Hodgkin’s lymphoma, sickle cell disease and diabetes mellitus

Abstract EN

Sickle cell disease (SCD) is an inherited defect in the synthesis of hemoglobin characterized by the change of glutamic acid by valine at position 6 in the beta globin chain of hemoglobin.

This simple change leads to a disease that affects organs such as the brain, eyes, lungs, kidneys and liver.

The disease affects millions of people worldwide with a high prevalence in the Middle East.

Type 2 diabetes mellitus (DM) also affects millions of people and is caused by a decreased production of insulin by beta cells in the pancreas.

Both diseases have a high prevalence in Bahrain, but the association is rare.

Hodgkin lymphoma (HL) is a relatively uncommon disease with a high clinical and epidemiological variability.

Its association with SCD has been described in few reports.