Antioxidant activity of 2-amino-4-(3,4-dichlorophenyl)‎-5-oxo-4, 5-dihydropyrano (3, 2-c)‎ chromene-3-carbonitrile compounds

Joint Authors

al-Amiri, Ahmad A.
al-Majidi, Yasamin K.
Abid, Talib K.
Rida, Khalid S.
Ibrahim, Hibah H.

Source

Engineering and Technology Journal

Publisher

University of Technology

Publication Date

2018-02-28

Country of Publication

Iraq

No. of Pages

5

Main Subjects

Earth Sciences, Water and Environment

English Abstract

Syntheses of coumarins, which are a structurally interesting antioxidant activity, was done in this article.

The modification of 4-hydroxycoumarin by different reaction steps was done to yield target compounds.

The structures of the synthesized compounds were characterized by spectroscopic methods, Infrared Spectra FT-IR and 1H and 13C Nuclear Magnetic Resonance Spectra and elemental analysis techniques, melting point and thin layer chromatography.

The antioxidant activities of individual compounds were tested against hydrogen peroxide (H2O2) and ferric reducing antioxidant power (FRAP) and the results were compared to the ascorbic acid and trolox as standards.

The results show that hydrogen peroxide scavenging activity of compounds 2and 3 are higher than that of the standard, and the values are 81.1±1.0%, and 82.3±1.5%, respectively and the compounds 1 and 4show scavenging activity on hydrogen peroxide with lower value compared with ascorbic acid..

Data Type

Conference Papers

Record ID

BIM-839502

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