Effects of aging on some enzyme biochemical related to oxidation in serum of local cows

Abstract EN

The study was included 90 local cows from Al-Rashidea area which locates in the east of Baghdad city, distributed into three groups, the smallest aged group (30) cows (1.5-2 ) years, middle aged group (30) cows (5.5-7) years and the older aged group (30) cows (11-13) years to study the effect progressing of age on some biochemical Criterias as indicators of oxidative stress.

The results revealed that the antioxidant enzymes, Glutathione -S-transferase GST was increased significantly (p<0.05) ) in middle -aged group And lower value in the older aging , it was noticed that arylesterase enzyme gradually decreased significantly with age progress.

The non enzymatic antioxidants such as Glutathione GSH revealed with the higher great value in the middle age group and the lower significant value in the aging compared with other groups.

on the other hand Malondialdehyde (MDA) and peroxy nitrite(ONOO-) level gradually increased with progressing of age, these events because of an increasing in production of free radicals and oxidative stress accompanied with processing of age due to antioxidants depletion, which consider as a defense line of body against the free radicals effects.

It was concluded from this study that with aging processes have harm effects on blood components diagnosed by reducing in antioxidants levels and increasing of Malondialdehyde and peroxy nitrite which consider as an indicators of oxidative stress and this support the theory of free radicals and oxidative stress and their role in aging processes .

Study the effect of aging on some biochemical parameters and antioxidant in cow.